Browse CCR7

Summary
SymbolCCR7
Namechemokine (C-C motif) receptor 7
Aliases BLR2; CDw197; CD197; CMKBR7; EBI1; CC-CKR-7; CCR-7; Bukitt's lymphoma receptor 2; CC chemokine receptor 7; E ......
Chromosomal Location17q12-q21.2
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Content Basic function annotation.
> Subcellular Location, Domain and Function
> Gene Ontology
> KEGG and Reactome Pathway
> Subcellular Location, Domain and Function
 
Subcellular Location Cell membrane; Multi-pass membrane protein.
Domain PF00001 7 transmembrane receptor (rhodopsin family)
Function

Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions.

> Gene Ontology
 
Biological Process GO:0000302 response to reactive oxygen species
GO:0001767 establishment of lymphocyte polarity
GO:0001768 establishment of T cell polarity
GO:0001771 immunological synapse formation
GO:0001819 positive regulation of cytokine production
GO:0001952 regulation of cell-matrix adhesion
GO:0001954 positive regulation of cell-matrix adhesion
GO:0002237 response to molecule of bacterial origin
GO:0002407 dendritic cell chemotaxis
GO:0002408 myeloid dendritic cell chemotaxis
GO:0002429 immune response-activating cell surface receptor signaling pathway
GO:0002437 inflammatory response to antigenic stimulus
GO:0002438 acute inflammatory response to antigenic stimulus
GO:0002468 dendritic cell antigen processing and presentation
GO:0002521 leukocyte differentiation
GO:0002524 hypersensitivity
GO:0002526 acute inflammatory response
GO:0002573 myeloid leukocyte differentiation
GO:0002577 regulation of antigen processing and presentation
GO:0002579 positive regulation of antigen processing and presentation
GO:0002604 regulation of dendritic cell antigen processing and presentation
GO:0002606 positive regulation of dendritic cell antigen processing and presentation
GO:0002673 regulation of acute inflammatory response
GO:0002675 positive regulation of acute inflammatory response
GO:0002685 regulation of leukocyte migration
GO:0002687 positive regulation of leukocyte migration
GO:0002688 regulation of leukocyte chemotaxis
GO:0002690 positive regulation of leukocyte chemotaxis
GO:0002694 regulation of leukocyte activation
GO:0002696 positive regulation of leukocyte activation
GO:0002757 immune response-activating signal transduction
GO:0002764 immune response-regulating signaling pathway
GO:0002768 immune response-regulating cell surface receptor signaling pathway
GO:0002861 regulation of inflammatory response to antigenic stimulus
GO:0002863 positive regulation of inflammatory response to antigenic stimulus
GO:0002864 regulation of acute inflammatory response to antigenic stimulus
GO:0002866 positive regulation of acute inflammatory response to antigenic stimulus
GO:0002883 regulation of hypersensitivity
GO:0002885 positive regulation of hypersensitivity
GO:0002920 regulation of humoral immune response
GO:0002922 positive regulation of humoral immune response
GO:0006644 phospholipid metabolic process
GO:0006816 calcium ion transport
GO:0006874 cellular calcium ion homeostasis
GO:0006875 cellular metal ion homeostasis
GO:0006959 humoral immune response
GO:0006979 response to oxidative stress
GO:0007015 actin filament organization
GO:0007159 leukocyte cell-cell adhesion
GO:0007160 cell-matrix adhesion
GO:0007163 establishment or maintenance of cell polarity
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0007249 I-kappaB kinase/NF-kappaB signaling
GO:0007254 JNK cascade
GO:0008037 cell recognition
GO:0008064 regulation of actin polymerization or depolymerization
GO:0008154 actin polymerization or depolymerization
GO:0009100 glycoprotein metabolic process
GO:0009101 glycoprotein biosynthetic process
GO:0009306 protein secretion
GO:0009988 cell-cell recognition
GO:0010035 response to inorganic substance
GO:0010559 regulation of glycoprotein biosynthetic process
GO:0010560 positive regulation of glycoprotein biosynthetic process
GO:0010810 regulation of cell-substrate adhesion
GO:0010811 positive regulation of cell-substrate adhesion
GO:0019216 regulation of lipid metabolic process
GO:0019882 antigen processing and presentation
GO:0022407 regulation of cell-cell adhesion
GO:0022409 positive regulation of cell-cell adhesion
GO:0030010 establishment of cell polarity
GO:0030031 cell projection assembly
GO:0030041 actin filament polymerization
GO:0030098 lymphocyte differentiation
GO:0030099 myeloid cell differentiation
GO:0030217 T cell differentiation
GO:0030335 positive regulation of cell migration
GO:0030593 neutrophil chemotaxis
GO:0030595 leukocyte chemotaxis
GO:0030832 regulation of actin filament length
GO:0030833 regulation of actin filament polymerization
GO:0030838 positive regulation of actin filament polymerization
GO:0031098 stress-activated protein kinase signaling cascade
GO:0031268 pseudopodium organization
GO:0031269 pseudopodium assembly
GO:0031272 regulation of pseudopodium assembly
GO:0031274 positive regulation of pseudopodium assembly
GO:0031294 lymphocyte costimulation
GO:0031295 T cell costimulation
GO:0031334 positive regulation of protein complex assembly
GO:0031346 positive regulation of cell projection organization
GO:0031349 positive regulation of defense response
GO:0031529 ruffle organization
GO:0031589 cell-substrate adhesion
GO:0032103 positive regulation of response to external stimulus
GO:0032271 regulation of protein polymerization
GO:0032273 positive regulation of protein polymerization
GO:0032496 response to lipopolysaccharide
GO:0032535 regulation of cellular component size
GO:0032609 interferon-gamma production
GO:0032611 interleukin-1 beta production
GO:0032612 interleukin-1 production
GO:0032615 interleukin-12 production
GO:0032649 regulation of interferon-gamma production
GO:0032651 regulation of interleukin-1 beta production
GO:0032652 regulation of interleukin-1 production
GO:0032655 regulation of interleukin-12 production
GO:0032735 positive regulation of interleukin-12 production
GO:0032844 regulation of homeostatic process
GO:0032845 negative regulation of homeostatic process
GO:0032872 regulation of stress-activated MAPK cascade
GO:0032874 positive regulation of stress-activated MAPK cascade
GO:0032956 regulation of actin cytoskeleton organization
GO:0032970 regulation of actin filament-based process
GO:0033077 T cell differentiation in thymus
GO:0033674 positive regulation of kinase activity
GO:0034694 response to prostaglandin
GO:0034695 response to prostaglandin E
GO:0036336 dendritic cell migration
GO:0038115 chemokine (C-C motif) ligand 19 signaling pathway
GO:0038116 chemokine (C-C motif) ligand 21 signaling pathway
GO:0040017 positive regulation of locomotion
GO:0042110 T cell activation
GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043254 regulation of protein complex assembly
GO:0043383 negative T cell selection
GO:0043410 positive regulation of MAPK cascade
GO:0043491 protein kinase B signaling
GO:0043550 regulation of lipid kinase activity
GO:0043551 regulation of phosphatidylinositol 3-kinase activity
GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity
GO:0044089 positive regulation of cellular component biogenesis
GO:0045058 T cell selection
GO:0045060 negative thymic T cell selection
GO:0045061 thymic T cell selection
GO:0045785 positive regulation of cell adhesion
GO:0045834 positive regulation of lipid metabolic process
GO:0045860 positive regulation of protein kinase activity
GO:0046328 regulation of JNK cascade
GO:0046330 positive regulation of JNK cascade
GO:0046847 filopodium assembly
GO:0048872 homeostasis of number of cells
GO:0050663 cytokine secretion
GO:0050701 interleukin-1 secretion
GO:0050702 interleukin-1 beta secretion
GO:0050704 regulation of interleukin-1 secretion
GO:0050706 regulation of interleukin-1 beta secretion
GO:0050707 regulation of cytokine secretion
GO:0050708 regulation of protein secretion
GO:0050727 regulation of inflammatory response
GO:0050729 positive regulation of inflammatory response
GO:0050851 antigen receptor-mediated signaling pathway
GO:0050852 T cell receptor signaling pathway
GO:0050854 regulation of antigen receptor-mediated signaling pathway
GO:0050856 regulation of T cell receptor signaling pathway
GO:0050857 positive regulation of antigen receptor-mediated signaling pathway
GO:0050862 positive regulation of T cell receptor signaling pathway
GO:0050863 regulation of T cell activation
GO:0050865 regulation of cell activation
GO:0050867 positive regulation of cell activation
GO:0050870 positive regulation of T cell activation
GO:0050900 leukocyte migration
GO:0050920 regulation of chemotaxis
GO:0050921 positive regulation of chemotaxis
GO:0051208 sequestering of calcium ion
GO:0051209 release of sequestered calcium ion into cytosol
GO:0051235 maintenance of location
GO:0051238 sequestering of metal ion
GO:0051249 regulation of lymphocyte activation
GO:0051251 positive regulation of lymphocyte activation
GO:0051258 protein polymerization
GO:0051272 positive regulation of cellular component movement
GO:0051282 regulation of sequestering of calcium ion
GO:0051283 negative regulation of sequestering of calcium ion
GO:0051403 stress-activated MAPK cascade
GO:0051480 regulation of cytosolic calcium ion concentration
GO:0051489 regulation of filopodium assembly
GO:0051491 positive regulation of filopodium assembly
GO:0051493 regulation of cytoskeleton organization
GO:0051495 positive regulation of cytoskeleton organization
GO:0051896 regulation of protein kinase B signaling
GO:0051897 positive regulation of protein kinase B signaling
GO:0055074 calcium ion homeostasis
GO:0060326 cell chemotaxis
GO:0060401 cytosolic calcium ion transport
GO:0060402 calcium ion transport into cytosol
GO:0060491 regulation of cell projection assembly
GO:0070098 chemokine-mediated signaling pathway
GO:0070302 regulation of stress-activated protein kinase signaling cascade
GO:0070304 positive regulation of stress-activated protein kinase signaling cascade
GO:0070371 ERK1 and ERK2 cascade
GO:0070372 regulation of ERK1 and ERK2 cascade
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0070486 leukocyte aggregation
GO:0070489 T cell aggregation
GO:0070509 calcium ion import
GO:0070588 calcium ion transmembrane transport
GO:0070838 divalent metal ion transport
GO:0071593 lymphocyte aggregation
GO:0071594 thymocyte aggregation
GO:0071621 granulocyte chemotaxis
GO:0071622 regulation of granulocyte chemotaxis
GO:0071624 positive regulation of granulocyte chemotaxis
GO:0071731 response to nitric oxide
GO:0071887 leukocyte apoptotic process
GO:0072503 cellular divalent inorganic cation homeostasis
GO:0072507 divalent inorganic cation homeostasis
GO:0072511 divalent inorganic cation transport
GO:0072610 interleukin-12 secretion
GO:0072676 lymphocyte migration
GO:0090022 regulation of neutrophil chemotaxis
GO:0090023 positive regulation of neutrophil chemotaxis
GO:0090066 regulation of anatomical structure size
GO:0090218 positive regulation of lipid kinase activity
GO:0090630 activation of GTPase activity
GO:0097021 lymphocyte migration into lymphoid organs
GO:0097022 lymphocyte migration into lymph node
GO:0097026 dendritic cell dendrite assembly
GO:0097028 dendritic cell differentiation
GO:0097029 mature conventional dendritic cell differentiation
GO:0097529 myeloid leukocyte migration
GO:0097530 granulocyte migration
GO:0097553 calcium ion transmembrane import into cytosol
GO:1901654 response to ketone
GO:1902622 regulation of neutrophil migration
GO:1902624 positive regulation of neutrophil migration
GO:1902656 calcium ion import into cytosol
GO:1903018 regulation of glycoprotein metabolic process
GO:1903020 positive regulation of glycoprotein metabolic process
GO:1903037 regulation of leukocyte cell-cell adhesion
GO:1903039 positive regulation of leukocyte cell-cell adhesion
GO:1903725 regulation of phospholipid metabolic process
GO:1903727 positive regulation of phospholipid metabolic process
GO:1990266 neutrophil migration
GO:2000021 regulation of ion homeostasis
GO:2000106 regulation of leukocyte apoptotic process
GO:2000107 negative regulation of leukocyte apoptotic process
GO:2000147 positive regulation of cell motility
GO:2000508 regulation of dendritic cell chemotaxis
GO:2000510 positive regulation of dendritic cell chemotaxis
GO:2000520 regulation of immunological synapse formation
GO:2000522 positive regulation of immunological synapse formation
GO:2000523 regulation of T cell costimulation
GO:2000525 positive regulation of T cell costimulation
GO:2000526 positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation
GO:2000547 regulation of dendritic cell dendrite assembly
Molecular Function GO:0001637 G-protein coupled chemoattractant receptor activity
GO:0001653 peptide receptor activity
GO:0004896 cytokine receptor activity
GO:0004950 chemokine receptor activity
GO:0008528 G-protein coupled peptide receptor activity
GO:0016493 C-C chemokine receptor activity
GO:0019955 cytokine binding
GO:0019956 chemokine binding
GO:0019957 C-C chemokine binding
GO:0035757 chemokine (C-C motif) ligand 19 binding
GO:0035758 chemokine (C-C motif) ligand 21 binding
GO:0038117 C-C motif chemokine 19 receptor activity
GO:0038121 C-C motif chemokine 21 receptor activity
Cellular Component GO:0009897 external side of plasma membrane
GO:0098552 side of membrane
> KEGG and Reactome Pathway
 
KEGG hsa04060 Cytokine-cytokine receptor interaction
hsa04062 Chemokine signaling pathway
Reactome R-HSA-380108: Chemokine receptors bind chemokines
R-HSA-373076: Class A/1 (Rhodopsin-like receptors)
R-HSA-418594: G alpha (i) signalling events
R-HSA-388396: GPCR downstream signaling
R-HSA-500792: GPCR ligand binding
R-HSA-375276: Peptide ligand-binding receptors
R-HSA-162582: Signal Transduction
R-HSA-372790: Signaling by GPCR
Summary
SymbolCCR7
Namechemokine (C-C motif) receptor 7
Aliases BLR2; CDw197; CD197; CMKBR7; EBI1; CC-CKR-7; CCR-7; Bukitt's lymphoma receptor 2; CC chemokine receptor 7; E ......
Chromosomal Location17q12-q21.2
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Content Literatures that report relations between CCR7 and anti-tumor immunity. The specific mechanism were also collected if the literature reports that a gene specifically promotes or inhibits the infiltration or function of T/NK cells.
> Text Mining
 
  Literatures describing the relation between CCR7 and anti-tumor immunity in human cancer.
PMID Cancer type Relation to immunity Evidence sentences
29630987ovarian carcinomaPromote immunity (T cell function); increase the efficacy of immunotherapyThis was associated with skin production of CCR7 and CXCR4 at vaccination sites driving DC migration.
16990769leukemiaPromote immunity(infiltration)Anti-BCP-ALL T cells expressed CD49d and CXCR4 (implicated in the recruitment to bone marrow), and CD62L and CCR7 (involved in the migration to lymphoid organs). In accordance with this profile, T cells significantly migrated in response to the chemokines CXCL12 and CCL19.
Summary
SymbolCCR7
Namechemokine (C-C motif) receptor 7
Aliases BLR2; CDw197; CD197; CMKBR7; EBI1; CC-CKR-7; CCR-7; Bukitt's lymphoma receptor 2; CC chemokine receptor 7; E ......
Chromosomal Location17q12-q21.2
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Content High-throughput screening data (e.g. CRISPR-Cas9, shRNA and RNAi) for T cell-mediated killing. Genetic screen techniques can identify mechanisms of tumor cell resistance (e.g., PTPN2) and sensitivity (e.g., APLNR) to killing by cytotoxic T cells, the central effectors of anti-tumor immunity. After comprehensively searching, eight groups of screening data sets were collected in the current database. In this tab, users can check whether their selected genes cause resistance or increase sensitivity to T cell-mediated killing in various data sets.
> High-throughput Screening
  Statistical results of CCR7 in screening data sets for detecting immune reponses.
PMID Screening System Cancer Type Cell Line Data Set Statistical Results Relation to immunity
29301958CRISPR-Cas9 melanomaB16F10Pmel-1 T cell NA/NS NA/NS
29301958CRISPR-Cas9 melanomaB16F10OT-1 T cell NA/NS NA/NS
28783722CRISPR-Cas9 melanomaMel6242CT-CRISPR NA/NS NA/NS
28723893CRISPR-Cas9 melanomaB16GVAX+Anti-PD1 NA/NS NA/NS
28723893CRISPR-Cas9 melanomaB16GVAX NA/NS NA/NS
25691366RNAiBreast cancerMCF7Luc-CTL assay NA Resistant to T cell-mediated killing
24476824shRNAmelanomaB16Primary screen NA/NS NA/NS
24476824shRNAmelanomaB16Secondary screen NA/NS NA/NS
Summary
SymbolCCR7
Namechemokine (C-C motif) receptor 7
Aliases BLR2; CDw197; CD197; CMKBR7; EBI1; CC-CKR-7; CCR-7; Bukitt's lymphoma receptor 2; CC chemokine receptor 7; E ......
Chromosomal Location17q12-q21.2
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Content Transcriptomic and genomic profiling of pre-treated tumor biopsies from responders and non-responders to immunotherapy. These data were used to identify signatures and mechanisms of response to checkpoint blockade (e.g., anti-PDL1 and anti-PD1). One example is that mutations in the gene PBRM1 benefit clinical survival of patients with clear cell renal cell carcinoma. After comprehensively searching, we collected 5 and 6 of transcriptomic and genomic data sets, respectively. In this tab, users can check whether their selected genes have significant difference of expression or mutation between responders and non-responders in various data sets.
> Expression difference between responders and non-responders
> Mutation difference between responders and non-responders
> Expression difference between responders and non-responders
 
Points in the above scatter plot represent the expression difference of CCR7 in various data sets.
No PMID Cancer type Group Drug # Res # NRes Log2 (Fold Change) P value Anno
126997480MelanomaallAnti-PD-1 (pembrolizumab and nivolumab)14120.9410.213
226997480MelanomaMAPKiAnti-PD-1 (pembrolizumab and nivolumab)652.0540.116
326997480Melanomanon-MAPKiAnti-PD-1 (pembrolizumab and nivolumab)870.1160.923
428552987Urothelial cancerallAnti-PD-L1 (atezolizumab) 9160.1310.868
528552987Urothelial cancersmokingAnti-PD-L1 (atezolizumab) 59-0.2530.865
628552987Urothelial cancernon-smokingAnti-PD-L1 (atezolizumab) 470.6330.767
729033130MelanomaallAnti-PD-1 (nivolumab) 26231.8660.0255
829033130MelanomaNIV3-PROGAnti-PD-1 (nivolumab) 15112.430.0469
929033130MelanomaNIV3-NAIVEAnti-PD-1 (nivolumab) 11121.3110.314
1029301960Clear cell renal cell carcinoma (ccRCC)allAnti-PD-1 (nivolumab) 482.5480.00505
1129301960Clear cell renal cell carcinoma (ccRCC)VEGFRiAnti-PD-1 (nivolumab) 2001
1229301960Clear cell renal cell carcinoma (ccRCC)non-VEGFRiAnti-PD-1 (nivolumab) 282.1310.132
1329443960Urothelial cancerallAnti-PD-L1 (atezolizumab) 68230-0.2260.424
> Mutation difference between responders and non-responders
 
Points in the above scatter plot represent the mutation difference of CCR7 in various data sets.
No PMID Cancer type Group Drug # Res # NRes % Mut/Res % Mut/NRes % Diff (R vs NR) Pval Anno
125765070Non-small cell lung cancer (NSCLC)allAnti-PD-1 (pembrolizumab) 14170001
225765070Non-small cell lung cancer (NSCLC)smokingAnti-PD-1 (pembrolizumab) 1030001
325765070Non-small cell lung cancer (NSCLC)non-smokingAnti-PD-1 (pembrolizumab) 4140001
426359337MelanomaallAnti-CTLA-4 (ipilimumab) 277301.4-1.41
526359337MelanomaBRAFiAnti-CTLA-4 (ipilimumab) 0140001
626359337Melanomanon-BRAFiAnti-CTLA-4 (ipilimumab) 275901.7-1.71
726997480MelanomaallAnti-PD-1 (pembrolizumab and nivolumab)21174.85.9-1.11
826997480MelanomaMAPKiAnti-PD-1 (pembrolizumab and nivolumab)860001
926997480Melanomanon-MAPKiAnti-PD-1 (pembrolizumab and nivolumab)13117.79.1-1.41
1028552987Urothelial cancerallAnti-PD-L1 (atezolizumab) 91606.2-6.21
1128552987Urothelial cancersmokingAnti-PD-L1 (atezolizumab) 59011.1-11.11
1228552987Urothelial cancernon-smokingAnti-PD-L1 (atezolizumab) 470001
1329033130MelanomaallAnti-PD-1 (nivolumab) 38272.63.7-1.11
1429033130MelanomaNIV3-PROGAnti-PD-1 (nivolumab) 22134.57.7-3.21
1529033130MelanomaNIV3-NAIVEAnti-PD-1 (nivolumab) 16140001
1629301960Clear cell renal cell carcinoma (ccRCC)allAnti-PD-1 (nivolumab) 11130001
1729301960Clear cell renal cell carcinoma (ccRCC)VEGFRiAnti-PD-1 (nivolumab) 610001
1829301960Clear cell renal cell carcinoma (ccRCC)non-VEGFRiAnti-PD-1 (nivolumab) 5120001
Summary
SymbolCCR7
Namechemokine (C-C motif) receptor 7
Aliases BLR2; CDw197; CD197; CMKBR7; EBI1; CC-CKR-7; CCR-7; Bukitt's lymphoma receptor 2; CC chemokine receptor 7; E ......
Chromosomal Location17q12-q21.2
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Content Relations between abundance of tumor-infiltrating lymphocytes (TILs) and expression, copy number, methylation, or mutation of CCR7. The immune-related signatures of 28 TIL types from Charoentong's study, which can be viewed in the download page. For each cancer type, the relative abundance of TILs were inferred by using gene set variation analysis (GSVA) based on gene expression profile. In this tab, users can examine which kinds of TILs might be regulated by the current gene.
> Lymphocyte
 
Summary
SymbolCCR7
Namechemokine (C-C motif) receptor 7
Aliases BLR2; CDw197; CD197; CMKBR7; EBI1; CC-CKR-7; CCR-7; Bukitt's lymphoma receptor 2; CC chemokine receptor 7; E ......
Chromosomal Location17q12-q21.2
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Content Relations between three kinds of immunomodulators and expression, copy number, methylation, or mutation of CCR7. These immunomo-dulators were collected from Charoentong's study. In this tab, users can examine which immunomodulators might be regulated by CCR7.
> Immunoinhibitor
> Immunostimulator
> MHC molecule
> Immunoinhibitor
 
> Immunostimulator
 
> MHC molecule
 
Summary
SymbolCCR7
Namechemokine (C-C motif) receptor 7
Aliases BLR2; CDw197; CD197; CMKBR7; EBI1; CC-CKR-7; CCR-7; Bukitt's lymphoma receptor 2; CC chemokine receptor 7; E ......
Chromosomal Location17q12-q21.2
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Content Relations between chemokines (or receptors) and expression, copy number, methylation, or mutation of CCR7. In this tab, users can examine which chemokines (or receptors) might be regulated by the current gene.
> Chemokine
> Receptor
> Chemokine
 
> Receptor
 
Summary
SymbolCCR7
Namechemokine (C-C motif) receptor 7
Aliases BLR2; CDw197; CD197; CMKBR7; EBI1; CC-CKR-7; CCR-7; Bukitt's lymphoma receptor 2; CC chemokine receptor 7; E ......
Chromosomal Location17q12-q21.2
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Content Distribution of CCR7 expression across immune and molecular subtypes.
> Immune subtype
> Molecular subtype
> Immune subtype
 
> Molecular subtype
 
Summary
SymbolCCR7
Namechemokine (C-C motif) receptor 7
Aliases BLR2; CDw197; CD197; CMKBR7; EBI1; CC-CKR-7; CCR-7; Bukitt's lymphoma receptor 2; CC chemokine receptor 7; E ......
Chromosomal Location17q12-q21.2
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Content Associations between CCR7 and clinical features.
> Overall survival analysis
> Cancer stage
> Tumor grade
> Overall survival
 
> Stage
 
> Grade
 
Summary
SymbolCCR7
Namechemokine (C-C motif) receptor 7
Aliases BLR2; CDw197; CD197; CMKBR7; EBI1; CC-CKR-7; CCR-7; Bukitt's lymphoma receptor 2; CC chemokine receptor 7; E ......
Chromosomal Location17q12-q21.2
External Links HGNC, NCBI, Ensembl, Uniprot, GeneCards
Content Drugs targeting CCR7 collected from DrugBank database.
> Drugs from DrugBank database
 

There is no record.