Summary | |
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Symbol | CEACAM1 |
Name | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
Aliases | BGP1; CD66a; BGPI; CD66a antigen; antigen CD66; CD antigen CD66a; BGP-1; Biliary glycoprotein 1; Carcinoembr ...... |
Chromosomal Location | 19q13.2 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Content |
Basic function annotation. > Subcellular Location, Domain and Function > Gene Ontology > KEGG and Reactome Pathway |
Subcellular Location | Isoform 1: Cell membrane Single-pass type I membrane protein Lateral cell membrane Apical cell membrane Basal cell membrane Cell junction Cell junction, adherens junction Note=Canalicular domain of hepatocyte plasma membranes. Found as a mixture of monomer, dimer and oligomer in the plasma membrane. Occurs predominantly as cis-dimers and/or small cis-oligomers in the cell junction regions. Found as dimer in the solution. Predominantly localized to the lateral cell membranes. ; SUBCELLULAR LOCATION: Isoform 2: Secreted ; SUBCELLULAR LOCATION: Isoform 3: Secreted ; SUBCELLULAR LOCATION: Isoform 4: Secreted ; SUBCELLULAR LOCATION: Isoform 5: Cell membrane; Single-pass type I membrane protein.; SUBCELLULAR LOCATION: Isoform 6: Cell membrane; Single-pass type I membrane protein.; SUBCELLULAR LOCATION: Isoform 7: Cell membrane; Single-pass type I membrane protein.; SUBCELLULAR LOCATION: Isoform 8: Cell membrane Single-pass type I membrane protein Cytoplasmic vesicle, secretory vesicle membrane Lateral cell membrane Apical cell membrane Basal cell membrane Cell junction Cell junction, adherens junction Note=Predominantly localized to the lateral cell membranes. Found as a mixture of monomer, dimer and oligomer in the plasma membrane. Occurs predominantly as cis-dimers and/or small cis-oligomers in the cell junction regions (By similarity). Co-localizes with ANXA2 in secretory vesicles and with S100A10/p11 at the plasma membrane (PubMed:14522961). ; SUBCELLULAR LOCATION: Cell projection, microvillus membrane Single-pass type I membrane protein Apical cell membrane Single-pass type I membrane protein Note=Colocalizes with CEACAM20 at the apical brush border of intestinal cells. |
Domain |
PF00047 Immunoglobulin domain PF13895 Immunoglobulin domain PF07686 Immunoglobulin V-set domain |
Function |
Isoform 1: Cell adhesion protein that mediates homophilic cell adhesion in a calcium-independent manner (By similarity). Plays a role as coinhibitory receptor in immune response, insulin action and functions also as an activator during angiogenesis (PubMed:18424730, PubMed:23696226, PubMed:25363763). Its coinhibitory receptor function is phosphorylation- and PTPN6 -dependent, which in turn, suppress signal transduction of associated receptors by dephosphorylation of their downstream effectors. Plays a role in immune response, of T cells, natural killer (NK) and neutrophils (PubMed:18424730, PubMed:23696226). Upon TCR/CD3 complex stimulation, inhibits TCR-mediated cytotoxicity by blocking granule exocytosis by mediating homophilic binding to adjacent cells, allowing interaction with and phosphorylation by LCK and interaction with the TCR/CD3 complex which recruits PTPN6 resulting in dephosphorylation of CD247 and ZAP70 (PubMed:18424730). Also inhibits T cell proliferation and cytokine production through inhibition of JNK cascade and plays a crucial role in regulating autoimmunity and anti-tumor immunity by inhibiting T cell through its interaction with HAVCR2 (PubMed:25363763). Upon natural killer (NK) cells activation, inhibit KLRK1-mediated cytolysis of CEACAM1-bearing tumor cells by trans-homophilic interactions with CEACAM1 on the target cell and lead to cis-interaction between CEACAM1 and KLRK1, allowing PTPN6 recruitment and then VAV1 dephosphorylation (PubMed:23696226). Upon neutrophils activation negatively regulates IL1B production by recruiting PTPN6 to a SYK-TLR4-CEACAM1 complex, that dephosphorylates SYK, reducing the production of reactive oxygen species (ROS) and lysosome disruption, which in turn, reduces the activity of the inflammasome. Downregulates neutrophil production by acting as a coinhibitory receptor for CSF3R by downregulating the CSF3R-STAT3 pathway through recruitment of PTPN6 that dephosphorylates CSF3R (By similarity). Also regulates insulin action by promoting INS clearance and regulating lipogenesis in liver through regulating insulin signaling (By similarity). Upon INS stimulation, undergoes phosphorylation by INSR leading to INS clearance by increasing receptor-mediated insulin endocytosis. This inernalization promotes interaction with FASN leading to receptor-mediated insulin degradation and to reduction of FASN activity leading to negative regulation of fatty acid synthesis. INSR-mediated phosphorylation also provokes a down-regulation of cell proliferation through SHC1 interaction resulting in decrease coupling of SHC1 to the MAPK3/ERK1-MAPK1/ERK2 and phosphatidylinositol 3-kinase pathways (By similarity). Functions as activator in angiogenesis by promoting blood vessel remodeling through endothelial cell differentiation and migration and in arteriogenesis by increasing the number of collateral arteries and collateral vessel calibers after ischemia. Also regulates vascular permeability through the VEGFR2 signaling pathway resulting in control of nitric oxide production (By similarity). Downregulates cell growth in response to EGF through its interaction with SHC1 that mediates interaction with EGFR resulting in decrease coupling of SHC1 to the MAPK3/ERK1-MAPK1/ERK2 pathway (By similarity). Negatively regulates platelet aggregation by decreasing platelet adhesion on type I collagen through the GPVI-FcRgamma complex (By similarity). Inhibits cell migration and cell scattering through interaction with FLNA; interfers with the interaction of FLNA with RALA (PubMed:16291724). Mediates bile acid transport activity in a phosphorylation dependent manner (By similarity). Negatively regulates osteoclastogenesis (By similarity). ; FUNCTION: Isoform 8: Cell adhesion protein that mediates homophilic cell adhesion in a calcium-independent manner (By similarity). Promotes populations of T cells regulating IgA production and secretion associated with control of the commensal microbiota and resistance to enteropathogens (By similarity). |
Biological Process |
GO:0001525 angiogenesis GO:0001558 regulation of cell growth GO:0001570 vasculogenesis GO:0001667 ameboidal-type cell migration GO:0001818 negative regulation of cytokine production GO:0001889 liver development GO:0001906 cell killing GO:0001909 leukocyte mediated cytotoxicity GO:0001910 regulation of leukocyte mediated cytotoxicity GO:0001911 negative regulation of leukocyte mediated cytotoxicity GO:0001913 T cell mediated cytotoxicity GO:0001914 regulation of T cell mediated cytotoxicity GO:0001915 negative regulation of T cell mediated cytotoxicity GO:0001933 negative regulation of protein phosphorylation GO:0001974 blood vessel remodeling GO:0002011 morphogenesis of an epithelial sheet GO:0002040 sprouting angiogenesis GO:0002228 natural killer cell mediated immunity GO:0002250 adaptive immune response GO:0002263 cell activation involved in immune response GO:0002285 lymphocyte activation involved in immune response GO:0002286 T cell activation involved in immune response GO:0002347 response to tumor cell GO:0002366 leukocyte activation involved in immune response GO:0002418 immune response to tumor cell GO:0002420 natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002423 natural killer cell mediated immune response to tumor cell GO:0002429 immune response-activating cell surface receptor signaling pathway GO:0002443 leukocyte mediated immunity GO:0002449 lymphocyte mediated immunity GO:0002456 T cell mediated immunity GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002521 leukocyte differentiation GO:0002573 myeloid leukocyte differentiation GO:0002683 negative regulation of immune system process GO:0002694 regulation of leukocyte activation GO:0002695 negative regulation of leukocyte activation GO:0002697 regulation of immune effector process GO:0002698 negative regulation of immune effector process GO:0002703 regulation of leukocyte mediated immunity GO:0002704 negative regulation of leukocyte mediated immunity GO:0002706 regulation of lymphocyte mediated immunity GO:0002707 negative regulation of lymphocyte mediated immunity GO:0002709 regulation of T cell mediated immunity GO:0002710 negative regulation of T cell mediated immunity GO:0002715 regulation of natural killer cell mediated immunity GO:0002716 negative regulation of natural killer cell mediated immunity GO:0002757 immune response-activating signal transduction GO:0002761 regulation of myeloid leukocyte differentiation GO:0002762 negative regulation of myeloid leukocyte differentiation GO:0002764 immune response-regulating signaling pathway GO:0002768 immune response-regulating cell surface receptor signaling pathway GO:0002819 regulation of adaptive immune response GO:0002820 negative regulation of adaptive immune response GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002831 regulation of response to biotic stimulus GO:0002832 negative regulation of response to biotic stimulus GO:0002834 regulation of response to tumor cell GO:0002835 negative regulation of response to tumor cell GO:0002837 regulation of immune response to tumor cell GO:0002838 negative regulation of immune response to tumor cell GO:0002855 regulation of natural killer cell mediated immune response to tumor cell GO:0002856 negative regulation of natural killer cell mediated immune response to tumor cell GO:0002858 regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002859 negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0003013 circulatory system process GO:0003018 vascular process in circulatory system GO:0003158 endothelium development GO:0006469 negative regulation of protein kinase activity GO:0006631 fatty acid metabolic process GO:0006633 fatty acid biosynthetic process GO:0006820 anion transport GO:0006869 lipid transport GO:0006887 exocytosis GO:0006898 receptor-mediated endocytosis GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules GO:0007159 leukocyte cell-cell adhesion GO:0007162 negative regulation of cell adhesion GO:0007173 epidermal growth factor receptor signaling pathway GO:0007229 integrin-mediated signaling pathway GO:0007596 blood coagulation GO:0007599 hemostasis GO:0008015 blood circulation GO:0010543 regulation of platelet activation GO:0010544 negative regulation of platelet activation GO:0010565 regulation of cellular ketone metabolic process GO:0010594 regulation of endothelial cell migration GO:0010631 epithelial cell migration GO:0010632 regulation of epithelial cell migration GO:0010876 lipid localization GO:0014065 phosphatidylinositol 3-kinase signaling GO:0014066 regulation of phosphatidylinositol 3-kinase signaling GO:0015711 organic anion transport GO:0015718 monocarboxylic acid transport GO:0015721 bile acid and bile salt transport GO:0015849 organic acid transport GO:0015850 organic hydroxy compound transport GO:0016049 cell growth GO:0016053 organic acid biosynthetic process GO:0017157 regulation of exocytosis GO:0019216 regulation of lipid metabolic process GO:0019217 regulation of fatty acid metabolic process GO:0022407 regulation of cell-cell adhesion GO:0022408 negative regulation of cell-cell adhesion GO:0022612 gland morphogenesis GO:0030099 myeloid cell differentiation GO:0030168 platelet activation GO:0030193 regulation of blood coagulation GO:0030195 negative regulation of blood coagulation GO:0030851 granulocyte differentiation GO:0030852 regulation of granulocyte differentiation GO:0030853 negative regulation of granulocyte differentiation GO:0030856 regulation of epithelial cell differentiation GO:0031341 regulation of cell killing GO:0031342 negative regulation of cell killing GO:0031348 negative regulation of defense response GO:0031623 receptor internalization GO:0032102 negative regulation of response to external stimulus GO:0032612 interleukin-1 production GO:0032652 regulation of interleukin-1 production GO:0032692 negative regulation of interleukin-1 production GO:0032868 response to insulin GO:0032869 cellular response to insulin stimulus GO:0033673 negative regulation of kinase activity GO:0034103 regulation of tissue remodeling GO:0034109 homotypic cell-cell adhesion GO:0034110 regulation of homotypic cell-cell adhesion GO:0034111 negative regulation of homotypic cell-cell adhesion GO:0035726 common myeloid progenitor cell proliferation GO:0038016 insulin receptor internalization GO:0038127 ERBB signaling pathway GO:0038158 granulocyte colony-stimulating factor signaling pathway GO:0042058 regulation of epidermal growth factor receptor signaling pathway GO:0042110 T cell activation GO:0042180 cellular ketone metabolic process GO:0042267 natural killer cell mediated cytotoxicity GO:0042269 regulation of natural killer cell mediated cytotoxicity GO:0042304 regulation of fatty acid biosynthetic process GO:0042326 negative regulation of phosphorylation GO:0043112 receptor metabolic process GO:0043114 regulation of vascular permeability GO:0043116 negative regulation of vascular permeability GO:0043299 leukocyte degranulation GO:0043300 regulation of leukocyte degranulation GO:0043301 negative regulation of leukocyte degranulation GO:0043316 cytotoxic T cell degranulation GO:0043317 regulation of cytotoxic T cell degranulation GO:0043318 negative regulation of cytotoxic T cell degranulation GO:0043434 response to peptide hormone GO:0043542 endothelial cell migration GO:0044283 small molecule biosynthetic process GO:0044319 wound healing, spreading of cells GO:0045055 regulated exocytosis GO:0045088 regulation of innate immune response GO:0045446 endothelial cell differentiation GO:0045601 regulation of endothelial cell differentiation GO:0045637 regulation of myeloid cell differentiation GO:0045638 negative regulation of myeloid cell differentiation GO:0045717 negative regulation of fatty acid biosynthetic process GO:0045765 regulation of angiogenesis GO:0045824 negative regulation of innate immune response GO:0045833 negative regulation of lipid metabolic process GO:0045920 negative regulation of exocytosis GO:0045922 negative regulation of fatty acid metabolic process GO:0045953 negative regulation of natural killer cell mediated cytotoxicity GO:0046394 carboxylic acid biosynthetic process GO:0046890 regulation of lipid biosynthetic process GO:0046942 carboxylic acid transport GO:0048015 phosphatidylinositol-mediated signaling GO:0048017 inositol lipid-mediated signaling GO:0048514 blood vessel morphogenesis GO:0048732 gland development GO:0048771 tissue remodeling GO:0050673 epithelial cell proliferation GO:0050678 regulation of epithelial cell proliferation GO:0050680 negative regulation of epithelial cell proliferation GO:0050777 negative regulation of immune response GO:0050817 coagulation GO:0050818 regulation of coagulation GO:0050819 negative regulation of coagulation GO:0050851 antigen receptor-mediated signaling pathway GO:0050852 T cell receptor signaling pathway GO:0050854 regulation of antigen receptor-mediated signaling pathway GO:0050856 regulation of T cell receptor signaling pathway GO:0050858 negative regulation of antigen receptor-mediated signaling pathway GO:0050860 negative regulation of T cell receptor signaling pathway GO:0050863 regulation of T cell activation GO:0050865 regulation of cell activation GO:0050866 negative regulation of cell activation GO:0050868 negative regulation of T cell activation GO:0050878 regulation of body fluid levels GO:0050900 leukocyte migration GO:0051048 negative regulation of secretion GO:0051051 negative regulation of transport GO:0051055 negative regulation of lipid biosynthetic process GO:0051249 regulation of lymphocyte activation GO:0051250 negative regulation of lymphocyte activation GO:0051348 negative regulation of transferase activity GO:0060312 regulation of blood vessel remodeling GO:0060627 regulation of vesicle-mediated transport GO:0061008 hepaticobiliary system development GO:0061041 regulation of wound healing GO:0061045 negative regulation of wound healing GO:0070371 ERK1 and ERK2 cascade GO:0070372 regulation of ERK1 and ERK2 cascade GO:0070486 leukocyte aggregation GO:0070489 T cell aggregation GO:0070527 platelet aggregation GO:0071375 cellular response to peptide hormone stimulus GO:0071417 cellular response to organonitrogen compound GO:0071593 lymphocyte aggregation GO:0072330 monocarboxylic acid biosynthetic process GO:0072574 hepatocyte proliferation GO:0072575 epithelial cell proliferation involved in liver morphogenesis GO:0072576 liver morphogenesis GO:0090130 tissue migration GO:0090132 epithelium migration GO:0090330 regulation of platelet aggregation GO:0090331 negative regulation of platelet aggregation GO:0090504 epiboly GO:0090505 epiboly involved in wound healing GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules GO:1900046 regulation of hemostasis GO:1900047 negative regulation of hemostasis GO:1901142 insulin metabolic process GO:1901143 insulin catabolic process GO:1901184 regulation of ERBB signaling pathway GO:1901342 regulation of vasculature development GO:1901652 response to peptide GO:1901653 cellular response to peptide GO:1902105 regulation of leukocyte differentiation GO:1902106 negative regulation of leukocyte differentiation GO:1903034 regulation of response to wounding GO:1903035 negative regulation of response to wounding GO:1903037 regulation of leukocyte cell-cell adhesion GO:1903038 negative regulation of leukocyte cell-cell adhesion GO:1903305 regulation of regulated secretory pathway GO:1903306 negative regulation of regulated secretory pathway GO:1903385 regulation of homophilic cell adhesion GO:1903531 negative regulation of secretion by cell GO:1903670 regulation of sprouting angiogenesis GO:1903706 regulation of hemopoiesis GO:1903707 negative regulation of hemopoiesis GO:1904018 positive regulation of vasculature development GO:2000027 regulation of organ morphogenesis GO:2000345 regulation of hepatocyte proliferation GO:2000346 negative regulation of hepatocyte proliferation GO:2001212 regulation of vasculogenesis GO:2001214 positive regulation of vasculogenesis |
Molecular Function |
GO:0003779 actin binding GO:0005319 lipid transporter activity GO:0005342 organic acid transmembrane transporter activity GO:0008028 monocarboxylic acid transmembrane transporter activity GO:0015125 bile acid transmembrane transporter activity GO:0019902 phosphatase binding GO:0019903 protein phosphatase binding GO:0031005 filamin binding GO:0046943 carboxylic acid transmembrane transporter activity GO:1901618 organic hydroxy compound transmembrane transporter activity GO:1990782 protein tyrosine kinase binding |
Cellular Component |
GO:0009925 basal plasma membrane GO:0016323 basolateral plasma membrane GO:0016324 apical plasma membrane GO:0016328 lateral plasma membrane GO:0030133 transport vesicle GO:0030658 transport vesicle membrane GO:0030659 cytoplasmic vesicle membrane GO:0042101 T cell receptor complex GO:0043235 receptor complex GO:0045177 apical part of cell GO:0045178 basal part of cell GO:0098802 plasma membrane receptor complex |
KEGG | - |
Reactome |
R-HSA-202733: Cell surface interactions at the vascular wall R-HSA-1474244: Extracellular matrix organization R-HSA-1566977: Fibronectin matrix formation R-HSA-109582: Hemostasis R-HSA-168256: Immune System R-HSA-168249: Innate Immune System R-HSA-6798695: Neutrophil degranulation |
Summary | |
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Symbol | CEACAM1 |
Name | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
Aliases | BGP1; CD66a; BGPI; CD66a antigen; antigen CD66; CD antigen CD66a; BGP-1; Biliary glycoprotein 1; Carcinoembr ...... |
Chromosomal Location | 19q13.2 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Content | Literatures that report relations between CEACAM1 and anti-tumor immunity. The specific mechanism were also collected if the literature reports that a gene specifically promotes or inhibits the infiltration or function of T/NK cells. |
Literatures describing the relation between CEACAM1 and anti-tumor immunity in human cancer.
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Summary | |
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Symbol | CEACAM1 |
Name | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
Aliases | BGP1; CD66a; BGPI; CD66a antigen; antigen CD66; CD antigen CD66a; BGP-1; Biliary glycoprotein 1; Carcinoembr ...... |
Chromosomal Location | 19q13.2 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Content | High-throughput screening data (e.g. CRISPR-Cas9, shRNA and RNAi) for T cell-mediated killing. Genetic screen techniques can identify mechanisms of tumor cell resistance (e.g., PTPN2) and sensitivity (e.g., APLNR) to killing by cytotoxic T cells, the central effectors of anti-tumor immunity. After comprehensively searching, eight groups of screening data sets were collected in the current database. In this tab, users can check whether their selected genes cause resistance or increase sensitivity to T cell-mediated killing in various data sets. |
> High-throughput Screening
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Statistical results of CEACAM1 in screening data sets for detecting immune reponses.
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Summary | |
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Symbol | CEACAM1 |
Name | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
Aliases | BGP1; CD66a; BGPI; CD66a antigen; antigen CD66; CD antigen CD66a; BGP-1; Biliary glycoprotein 1; Carcinoembr ...... |
Chromosomal Location | 19q13.2 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Content |
Transcriptomic and genomic profiling of pre-treated tumor biopsies from responders and non-responders to immunotherapy. These data were used to identify signatures and mechanisms of response to checkpoint blockade (e.g., anti-PDL1 and anti-PD1). One example is that mutations in the gene PBRM1 benefit clinical survival of patients with clear cell renal cell carcinoma. After comprehensively searching, we collected 5 and 6 of transcriptomic and genomic data sets, respectively. In this tab, users can check whether their selected genes have significant difference of expression or mutation between responders and non-responders in various data sets. > Expression difference between responders and non-responders > Mutation difference between responders and non-responders |
Points in the above scatter plot represent the expression difference of CEACAM1 in various data sets.
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Points in the above scatter plot represent the mutation difference of CEACAM1 in various data sets.
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Summary | |
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Symbol | CEACAM1 |
Name | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
Aliases | BGP1; CD66a; BGPI; CD66a antigen; antigen CD66; CD antigen CD66a; BGP-1; Biliary glycoprotein 1; Carcinoembr ...... |
Chromosomal Location | 19q13.2 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Content |
Relations between abundance of tumor-infiltrating lymphocytes (TILs) and expression, copy number, methylation, or mutation of CEACAM1. The immune-related signatures of 28 TIL types from Charoentong's study, which can be viewed in the download page. For each cancer type, the relative abundance of TILs were inferred by using gene set variation analysis (GSVA) based on gene expression profile. In this tab, users can examine which kinds of TILs might be regulated by the current gene. |
Summary | |
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Symbol | CEACAM1 |
Name | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
Aliases | BGP1; CD66a; BGPI; CD66a antigen; antigen CD66; CD antigen CD66a; BGP-1; Biliary glycoprotein 1; Carcinoembr ...... |
Chromosomal Location | 19q13.2 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Content |
Relations between three kinds of immunomodulators and expression, copy number, methylation, or mutation of CEACAM1. These immunomo-dulators were collected from Charoentong's study. In this tab, users can examine which immunomodulators might be regulated by CEACAM1. > Immunoinhibitor > Immunostimulator > MHC molecule |
Summary | |
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Symbol | CEACAM1 |
Name | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
Aliases | BGP1; CD66a; BGPI; CD66a antigen; antigen CD66; CD antigen CD66a; BGP-1; Biliary glycoprotein 1; Carcinoembr ...... |
Chromosomal Location | 19q13.2 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Content |
Relations between chemokines (or receptors) and expression, copy number, methylation, or mutation of CEACAM1. In this tab, users can examine which chemokines (or receptors) might be regulated by the current gene. > Chemokine > Receptor |
Summary | |
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Symbol | CEACAM1 |
Name | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
Aliases | BGP1; CD66a; BGPI; CD66a antigen; antigen CD66; CD antigen CD66a; BGP-1; Biliary glycoprotein 1; Carcinoembr ...... |
Chromosomal Location | 19q13.2 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Content |
Distribution of CEACAM1 expression across immune and molecular subtypes. > Immune subtype > Molecular subtype |
Summary | |
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Symbol | CEACAM1 |
Name | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
Aliases | BGP1; CD66a; BGPI; CD66a antigen; antigen CD66; CD antigen CD66a; BGP-1; Biliary glycoprotein 1; Carcinoembr ...... |
Chromosomal Location | 19q13.2 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Content |
Associations between CEACAM1 and clinical features. > Overall survival analysis > Cancer stage > Tumor grade |
Summary | |
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Symbol | CEACAM1 |
Name | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
Aliases | BGP1; CD66a; BGPI; CD66a antigen; antigen CD66; CD antigen CD66a; BGP-1; Biliary glycoprotein 1; Carcinoembr ...... |
Chromosomal Location | 19q13.2 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Content | Drugs targeting CEACAM1 collected from DrugBank database. |
Details on drugs targeting CEACAM1.
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