Summary | |
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Symbol | FOXP3 |
Name | forkhead box P3 |
Aliases | JM2; XPID; AIID; PIDX; DIETER; SCURFIN; IPEX; immune dysregulation, polyendocrinopathy, enteropathy, X-linke ...... |
Chromosomal Location | Xp11.23 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Content |
Basic function annotation. > Subcellular Location, Domain and Function > Gene Ontology > KEGG and Reactome Pathway |
Subcellular Location | Nucleus Cytoplasm Note=Predominantly expressed in the cytoplasm in activated conventional T-cells whereas predominantly expressed in the nucleus in regulatory T-cells (Treg). The 41 kDa form derived by proteolytic processing is found exclusively in the chromatin fraction of activated Treg cells (By similarity). |
Domain |
PF00250 Forkhead domain PF16159 FOXP coiled-coil domain |
Function |
Transcriptional regulator which is crucial for the development and inhibitory function of regulatory T-cells (Treg). Plays an essential role in maintaining homeostasis of the immune system by allowing the acquisition of full suppressive function and stability of the Treg lineage, and by directly modulating the expansion and function of conventional T-cells. Can act either as a transcriptional repressor or a transcriptional activator depending on its interactions with other transcription factors, histone acetylases and deacetylases. The suppressive activity of Treg involves the coordinate activation of many genes, including CTLA4 and TNFRSF18 by FOXP3 along with repression of genes encoding cytokines such as interleukin-2 (IL2) and interferon-gamma (IFNG). Inhibits cytokine production and T-cell effector function by repressing the activity of two key transcription factors, RELA and NFATC2 (PubMed:15790681). Mediates transcriptional repression of IL2 via its association with histone acetylase KAT5 and histone deacetylase HDAC7 (PubMed:17360565). Can activate the expression of TNFRSF18, IL2RA and CTLA4 and repress the expression of IL2 and IFNG via its association with transcription factor RUNX1 (PubMed:17377532). Inhibits the differentiation of IL17 producing helper T-cells (Th17) by antagonizing RORC function, leading to down-regulation of IL17 expression, favoring Treg development (PubMed:18368049). Inhibits the transcriptional activator activity of RORA (PubMed:18354202). Can repress the expression of IL2 and IFNG via its association with transcription factor IKZF4 (By similarity). |
Biological Process |
GO:0000018 regulation of DNA recombination GO:0001776 leukocyte homeostasis GO:0001782 B cell homeostasis GO:0001818 negative regulation of cytokine production GO:0001819 positive regulation of cytokine production GO:0002200 somatic diversification of immune receptors GO:0002204 somatic recombination of immunoglobulin genes involved in immune response GO:0002208 somatic diversification of immunoglobulins involved in immune response GO:0002249 lymphocyte anergy GO:0002250 adaptive immune response GO:0002260 lymphocyte homeostasis GO:0002262 myeloid cell homeostasis GO:0002263 cell activation involved in immune response GO:0002285 lymphocyte activation involved in immune response GO:0002286 T cell activation involved in immune response GO:0002287 alpha-beta T cell activation involved in immune response GO:0002292 T cell differentiation involved in immune response GO:0002293 alpha-beta T cell differentiation involved in immune response GO:0002294 CD4-positive, alpha-beta T cell differentiation involved in immune response GO:0002312 B cell activation involved in immune response GO:0002360 T cell lineage commitment GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation GO:0002362 CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment GO:0002363 alpha-beta T cell lineage commitment GO:0002366 leukocyte activation involved in immune response GO:0002367 cytokine production involved in immune response GO:0002369 T cell cytokine production GO:0002377 immunoglobulin production GO:0002381 immunoglobulin production involved in immunoglobulin mediated immune response GO:0002429 immune response-activating cell surface receptor signaling pathway GO:0002440 production of molecular mediator of immune response GO:0002443 leukocyte mediated immunity GO:0002449 lymphocyte mediated immunity GO:0002456 T cell mediated immunity GO:0002458 peripheral T cell tolerance induction GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002461 tolerance induction dependent upon immune response GO:0002465 peripheral tolerance induction GO:0002507 tolerance induction GO:0002513 tolerance induction to self antigen GO:0002517 T cell tolerance induction GO:0002521 leukocyte differentiation GO:0002544 chronic inflammatory response GO:0002562 somatic diversification of immune receptors via germline recombination within a single locus GO:0002637 regulation of immunoglobulin production GO:0002638 negative regulation of immunoglobulin production GO:0002643 regulation of tolerance induction GO:0002645 positive regulation of tolerance induction GO:0002652 regulation of tolerance induction dependent upon immune response GO:0002654 positive regulation of tolerance induction dependent upon immune response GO:0002658 regulation of peripheral tolerance induction GO:0002660 positive regulation of peripheral tolerance induction GO:0002664 regulation of T cell tolerance induction GO:0002666 positive regulation of T cell tolerance induction GO:0002667 regulation of T cell anergy GO:0002669 positive regulation of T cell anergy GO:0002676 regulation of chronic inflammatory response GO:0002677 negative regulation of chronic inflammatory response GO:0002683 negative regulation of immune system process GO:0002694 regulation of leukocyte activation GO:0002695 negative regulation of leukocyte activation GO:0002696 positive regulation of leukocyte activation GO:0002697 regulation of immune effector process GO:0002698 negative regulation of immune effector process GO:0002699 positive regulation of immune effector process GO:0002700 regulation of production of molecular mediator of immune response GO:0002701 negative regulation of production of molecular mediator of immune response GO:0002703 regulation of leukocyte mediated immunity GO:0002704 negative regulation of leukocyte mediated immunity GO:0002705 positive regulation of leukocyte mediated immunity GO:0002706 regulation of lymphocyte mediated immunity GO:0002707 negative regulation of lymphocyte mediated immunity GO:0002708 positive regulation of lymphocyte mediated immunity GO:0002709 regulation of T cell mediated immunity GO:0002710 negative regulation of T cell mediated immunity GO:0002711 positive regulation of T cell mediated immunity GO:0002712 regulation of B cell mediated immunity GO:0002713 negative regulation of B cell mediated immunity GO:0002718 regulation of cytokine production involved in immune response GO:0002719 negative regulation of cytokine production involved in immune response GO:0002724 regulation of T cell cytokine production GO:0002725 negative regulation of T cell cytokine production GO:0002757 immune response-activating signal transduction GO:0002764 immune response-regulating signaling pathway GO:0002768 immune response-regulating cell surface receptor signaling pathway GO:0002819 regulation of adaptive immune response GO:0002820 negative regulation of adaptive immune response GO:0002821 positive regulation of adaptive immune response GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002849 regulation of peripheral T cell tolerance induction GO:0002851 positive regulation of peripheral T cell tolerance induction GO:0002870 T cell anergy GO:0002889 regulation of immunoglobulin mediated immune response GO:0002890 negative regulation of immunoglobulin mediated immune response GO:0002911 regulation of lymphocyte anergy GO:0002913 positive regulation of lymphocyte anergy GO:0006310 DNA recombination GO:0006338 chromatin remodeling GO:0006473 protein acetylation GO:0006475 internal protein amino acid acetylation GO:0006476 protein deacetylation GO:0007159 leukocyte cell-cell adhesion GO:0007162 negative regulation of cell adhesion GO:0009306 protein secretion GO:0009615 response to virus GO:0016064 immunoglobulin mediated immune response GO:0016444 somatic cell DNA recombination GO:0016445 somatic diversification of immunoglobulins GO:0016447 somatic recombination of immunoglobulin gene segments GO:0016570 histone modification GO:0016573 histone acetylation GO:0016575 histone deacetylation GO:0018205 peptidyl-lysine modification GO:0018393 internal peptidyl-lysine acetylation GO:0018394 peptidyl-lysine acetylation GO:0019724 B cell mediated immunity GO:0022407 regulation of cell-cell adhesion GO:0022408 negative regulation of cell-cell adhesion GO:0022409 positive regulation of cell-cell adhesion GO:0030098 lymphocyte differentiation GO:0030217 T cell differentiation GO:0031056 regulation of histone modification GO:0031057 negative regulation of histone modification GO:0031058 positive regulation of histone modification GO:0031063 regulation of histone deacetylation GO:0031064 negative regulation of histone deacetylation GO:0031348 negative regulation of defense response GO:0032088 negative regulation of NF-kappaB transcription factor activity GO:0032102 negative regulation of response to external stimulus GO:0032609 interferon-gamma production GO:0032613 interleukin-10 production GO:0032620 interleukin-17 production GO:0032623 interleukin-2 production GO:0032633 interleukin-4 production GO:0032634 interleukin-5 production GO:0032635 interleukin-6 production GO:0032640 tumor necrosis factor production GO:0032649 regulation of interferon-gamma production GO:0032653 regulation of interleukin-10 production GO:0032660 regulation of interleukin-17 production GO:0032663 regulation of interleukin-2 production GO:0032673 regulation of interleukin-4 production GO:0032674 regulation of interleukin-5 production GO:0032675 regulation of interleukin-6 production GO:0032680 regulation of tumor necrosis factor production GO:0032689 negative regulation of interferon-gamma production GO:0032693 negative regulation of interleukin-10 production GO:0032700 negative regulation of interleukin-17 production GO:0032703 negative regulation of interleukin-2 production GO:0032713 negative regulation of interleukin-4 production GO:0032714 negative regulation of interleukin-5 production GO:0032715 negative regulation of interleukin-6 production GO:0032720 negative regulation of tumor necrosis factor production GO:0032753 positive regulation of interleukin-4 production GO:0032792 negative regulation of CREB transcription factor activity GO:0032829 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation GO:0032831 positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation GO:0032905 transforming growth factor beta1 production GO:0032908 regulation of transforming growth factor beta1 production GO:0032914 positive regulation of transforming growth factor beta1 production GO:0032943 mononuclear cell proliferation GO:0032944 regulation of mononuclear cell proliferation GO:0032945 negative regulation of mononuclear cell proliferation GO:0032946 positive regulation of mononuclear cell proliferation GO:0033077 T cell differentiation in thymus GO:0033079 immature T cell proliferation GO:0033080 immature T cell proliferation in thymus GO:0033081 regulation of T cell differentiation in thymus GO:0033083 regulation of immature T cell proliferation GO:0033084 regulation of immature T cell proliferation in thymus GO:0033089 positive regulation of T cell differentiation in thymus GO:0033091 positive regulation of immature T cell proliferation GO:0033092 positive regulation of immature T cell proliferation in thymus GO:0035065 regulation of histone acetylation GO:0035066 positive regulation of histone acetylation GO:0035067 negative regulation of histone acetylation GO:0035601 protein deacylation GO:0035710 CD4-positive, alpha-beta T cell activation GO:0042035 regulation of cytokine biosynthetic process GO:0042036 negative regulation of cytokine biosynthetic process GO:0042089 cytokine biosynthetic process GO:0042093 T-helper cell differentiation GO:0042094 interleukin-2 biosynthetic process GO:0042095 interferon-gamma biosynthetic process GO:0042098 T cell proliferation GO:0042102 positive regulation of T cell proliferation GO:0042107 cytokine metabolic process GO:0042110 T cell activation GO:0042113 B cell activation GO:0042129 regulation of T cell proliferation GO:0042130 negative regulation of T cell proliferation GO:0043029 T cell homeostasis GO:0043367 CD4-positive, alpha-beta T cell differentiation GO:0043368 positive T cell selection GO:0043369 CD4-positive or CD8-positive, alpha-beta T cell lineage commitment GO:0043370 regulation of CD4-positive, alpha-beta T cell differentiation GO:0043371 negative regulation of CD4-positive, alpha-beta T cell differentiation GO:0043372 positive regulation of CD4-positive, alpha-beta T cell differentiation GO:0043373 CD4-positive, alpha-beta T cell lineage commitment GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity GO:0043543 protein acylation GO:0045058 T cell selection GO:0045066 regulatory T cell differentiation GO:0045072 regulation of interferon-gamma biosynthetic process GO:0045076 regulation of interleukin-2 biosynthetic process GO:0045077 negative regulation of interferon-gamma biosynthetic process GO:0045085 negative regulation of interleukin-2 biosynthetic process GO:0045165 cell fate commitment GO:0045190 isotype switching GO:0045191 regulation of isotype switching GO:0045580 regulation of T cell differentiation GO:0045581 negative regulation of T cell differentiation GO:0045582 positive regulation of T cell differentiation GO:0045589 regulation of regulatory T cell differentiation GO:0045591 positive regulation of regulatory T cell differentiation GO:0045619 regulation of lymphocyte differentiation GO:0045620 negative regulation of lymphocyte differentiation GO:0045621 positive regulation of lymphocyte differentiation GO:0045622 regulation of T-helper cell differentiation GO:0045623 negative regulation of T-helper cell differentiation GO:0045785 positive regulation of cell adhesion GO:0045829 negative regulation of isotype switching GO:0045910 negative regulation of DNA recombination GO:0046006 regulation of activated T cell proliferation GO:0046007 negative regulation of activated T cell proliferation GO:0046631 alpha-beta T cell activation GO:0046632 alpha-beta T cell differentiation GO:0046634 regulation of alpha-beta T cell activation GO:0046635 positive regulation of alpha-beta T cell activation GO:0046636 negative regulation of alpha-beta T cell activation GO:0046637 regulation of alpha-beta T cell differentiation GO:0046638 positive regulation of alpha-beta T cell differentiation GO:0046639 negative regulation of alpha-beta T cell differentiation GO:0046651 lymphocyte proliferation GO:0048289 isotype switching to IgE isotypes GO:0048291 isotype switching to IgG isotypes GO:0048293 regulation of isotype switching to IgE isotypes GO:0048294 negative regulation of isotype switching to IgE isotypes GO:0048302 regulation of isotype switching to IgG isotypes GO:0048872 homeostasis of number of cells GO:0050663 cytokine secretion GO:0050670 regulation of lymphocyte proliferation GO:0050671 positive regulation of lymphocyte proliferation GO:0050672 negative regulation of lymphocyte proliferation GO:0050707 regulation of cytokine secretion GO:0050708 regulation of protein secretion GO:0050709 negative regulation of protein secretion GO:0050710 negative regulation of cytokine secretion GO:0050727 regulation of inflammatory response GO:0050728 negative regulation of inflammatory response GO:0050777 negative regulation of immune response GO:0050798 activated T cell proliferation GO:0050851 antigen receptor-mediated signaling pathway GO:0050852 T cell receptor signaling pathway GO:0050863 regulation of T cell activation GO:0050864 regulation of B cell activation GO:0050865 regulation of cell activation GO:0050866 negative regulation of cell activation GO:0050867 positive regulation of cell activation GO:0050868 negative regulation of T cell activation GO:0050869 negative regulation of B cell activation GO:0050870 positive regulation of T cell activation GO:0051048 negative regulation of secretion GO:0051051 negative regulation of transport GO:0051052 regulation of DNA metabolic process GO:0051053 negative regulation of DNA metabolic process GO:0051090 regulation of sequence-specific DNA binding transcription factor activity GO:0051224 negative regulation of protein transport GO:0051249 regulation of lymphocyte activation GO:0051250 negative regulation of lymphocyte activation GO:0051251 positive regulation of lymphocyte activation GO:0070486 leukocyte aggregation GO:0070489 T cell aggregation GO:0070661 leukocyte proliferation GO:0070663 regulation of leukocyte proliferation GO:0070664 negative regulation of leukocyte proliferation GO:0070665 positive regulation of leukocyte proliferation GO:0071593 lymphocyte aggregation GO:0071594 thymocyte aggregation GO:0071604 transforming growth factor beta production GO:0071634 regulation of transforming growth factor beta production GO:0071636 positive regulation of transforming growth factor beta production GO:0071706 tumor necrosis factor superfamily cytokine production GO:0072538 T-helper 17 type immune response GO:0072539 T-helper 17 cell differentiation GO:0090311 regulation of protein deacetylation GO:0098732 macromolecule deacylation GO:1901983 regulation of protein acetylation GO:1901984 negative regulation of protein acetylation GO:1901985 positive regulation of protein acetylation GO:1902105 regulation of leukocyte differentiation GO:1902106 negative regulation of leukocyte differentiation GO:1902107 positive regulation of leukocyte differentiation GO:1902275 regulation of chromatin organization GO:1903037 regulation of leukocyte cell-cell adhesion GO:1903038 negative regulation of leukocyte cell-cell adhesion GO:1903039 positive regulation of leukocyte cell-cell adhesion GO:1903531 negative regulation of secretion by cell GO:1903555 regulation of tumor necrosis factor superfamily cytokine production GO:1903556 negative regulation of tumor necrosis factor superfamily cytokine production GO:1903706 regulation of hemopoiesis GO:1903707 negative regulation of hemopoiesis GO:1903708 positive regulation of hemopoiesis GO:1904950 negative regulation of establishment of protein localization GO:1905268 negative regulation of chromatin organization GO:1905269 positive regulation of chromatin organization GO:2000316 regulation of T-helper 17 type immune response GO:2000317 negative regulation of T-helper 17 type immune response GO:2000319 regulation of T-helper 17 cell differentiation GO:2000320 negative regulation of T-helper 17 cell differentiation GO:2000398 regulation of thymocyte aggregation GO:2000400 positive regulation of thymocyte aggregation GO:2000514 regulation of CD4-positive, alpha-beta T cell activation GO:2000515 negative regulation of CD4-positive, alpha-beta T cell activation GO:2000516 positive regulation of CD4-positive, alpha-beta T cell activation GO:2000756 regulation of peptidyl-lysine acetylation GO:2000757 negative regulation of peptidyl-lysine acetylation GO:2000758 positive regulation of peptidyl-lysine acetylation |
Molecular Function |
GO:0001047 core promoter binding GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding GO:0003714 transcription corepressor activity GO:0008134 transcription factor binding GO:0035035 histone acetyltransferase binding GO:0042826 histone deacetylase binding GO:0051059 NF-kappaB binding GO:0051525 NFAT protein binding |
Cellular Component | - |
KEGG | - |
Reactome | - |
Summary | |
---|---|
Symbol | FOXP3 |
Name | forkhead box P3 |
Aliases | JM2; XPID; AIID; PIDX; DIETER; SCURFIN; IPEX; immune dysregulation, polyendocrinopathy, enteropathy, X-linke ...... |
Chromosomal Location | Xp11.23 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Content | Literatures that report relations between FOXP3 and anti-tumor immunity. The specific mechanism were also collected if the literature reports that a gene specifically promotes or inhibits the infiltration or function of T/NK cells. |
Literatures describing the relation between FOXP3 and anti-tumor immunity in human cancer.
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Summary | |
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Symbol | FOXP3 |
Name | forkhead box P3 |
Aliases | JM2; XPID; AIID; PIDX; DIETER; SCURFIN; IPEX; immune dysregulation, polyendocrinopathy, enteropathy, X-linke ...... |
Chromosomal Location | Xp11.23 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Content | High-throughput screening data (e.g. CRISPR-Cas9, shRNA and RNAi) for T cell-mediated killing. Genetic screen techniques can identify mechanisms of tumor cell resistance (e.g., PTPN2) and sensitivity (e.g., APLNR) to killing by cytotoxic T cells, the central effectors of anti-tumor immunity. After comprehensively searching, eight groups of screening data sets were collected in the current database. In this tab, users can check whether their selected genes cause resistance or increase sensitivity to T cell-mediated killing in various data sets. |
> High-throughput Screening
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Statistical results of FOXP3 in screening data sets for detecting immune reponses.
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Summary | |
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Symbol | FOXP3 |
Name | forkhead box P3 |
Aliases | JM2; XPID; AIID; PIDX; DIETER; SCURFIN; IPEX; immune dysregulation, polyendocrinopathy, enteropathy, X-linke ...... |
Chromosomal Location | Xp11.23 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Content |
Transcriptomic and genomic profiling of pre-treated tumor biopsies from responders and non-responders to immunotherapy. These data were used to identify signatures and mechanisms of response to checkpoint blockade (e.g., anti-PDL1 and anti-PD1). One example is that mutations in the gene PBRM1 benefit clinical survival of patients with clear cell renal cell carcinoma. After comprehensively searching, we collected 5 and 6 of transcriptomic and genomic data sets, respectively. In this tab, users can check whether their selected genes have significant difference of expression or mutation between responders and non-responders in various data sets. > Expression difference between responders and non-responders > Mutation difference between responders and non-responders |
Points in the above scatter plot represent the expression difference of FOXP3 in various data sets.
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Points in the above scatter plot represent the mutation difference of FOXP3 in various data sets.
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Summary | |
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Symbol | FOXP3 |
Name | forkhead box P3 |
Aliases | JM2; XPID; AIID; PIDX; DIETER; SCURFIN; IPEX; immune dysregulation, polyendocrinopathy, enteropathy, X-linke ...... |
Chromosomal Location | Xp11.23 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Content |
Relations between abundance of tumor-infiltrating lymphocytes (TILs) and expression, copy number, methylation, or mutation of FOXP3. The immune-related signatures of 28 TIL types from Charoentong's study, which can be viewed in the download page. For each cancer type, the relative abundance of TILs were inferred by using gene set variation analysis (GSVA) based on gene expression profile. In this tab, users can examine which kinds of TILs might be regulated by the current gene. |
Summary | |
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Symbol | FOXP3 |
Name | forkhead box P3 |
Aliases | JM2; XPID; AIID; PIDX; DIETER; SCURFIN; IPEX; immune dysregulation, polyendocrinopathy, enteropathy, X-linke ...... |
Chromosomal Location | Xp11.23 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Content |
Relations between three kinds of immunomodulators and expression, copy number, methylation, or mutation of FOXP3. These immunomo-dulators were collected from Charoentong's study. In this tab, users can examine which immunomodulators might be regulated by FOXP3. > Immunoinhibitor > Immunostimulator > MHC molecule |
Summary | |
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Symbol | FOXP3 |
Name | forkhead box P3 |
Aliases | JM2; XPID; AIID; PIDX; DIETER; SCURFIN; IPEX; immune dysregulation, polyendocrinopathy, enteropathy, X-linke ...... |
Chromosomal Location | Xp11.23 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Content |
Relations between chemokines (or receptors) and expression, copy number, methylation, or mutation of FOXP3. In this tab, users can examine which chemokines (or receptors) might be regulated by the current gene. > Chemokine > Receptor |
Summary | |
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Symbol | FOXP3 |
Name | forkhead box P3 |
Aliases | JM2; XPID; AIID; PIDX; DIETER; SCURFIN; IPEX; immune dysregulation, polyendocrinopathy, enteropathy, X-linke ...... |
Chromosomal Location | Xp11.23 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Content |
Distribution of FOXP3 expression across immune and molecular subtypes. > Immune subtype > Molecular subtype |
Summary | |
---|---|
Symbol | FOXP3 |
Name | forkhead box P3 |
Aliases | JM2; XPID; AIID; PIDX; DIETER; SCURFIN; IPEX; immune dysregulation, polyendocrinopathy, enteropathy, X-linke ...... |
Chromosomal Location | Xp11.23 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Content |
Associations between FOXP3 and clinical features. > Overall survival analysis > Cancer stage > Tumor grade |
Summary | |
---|---|
Symbol | FOXP3 |
Name | forkhead box P3 |
Aliases | JM2; XPID; AIID; PIDX; DIETER; SCURFIN; IPEX; immune dysregulation, polyendocrinopathy, enteropathy, X-linke ...... |
Chromosomal Location | Xp11.23 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Content | Drugs targeting FOXP3 collected from DrugBank database. |
There is no record. |