Summary | |
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Symbol | IL12B |
Name | interleukin 12B |
Aliases | IL-12B; NKSF; CLMF2; natural killer cell stimulatory factor-2; cytotoxic lymphocyte maturation factor 2, p40 ...... |
Chromosomal Location | 5q33.3 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Content |
Basic function annotation. > Subcellular Location, Domain and Function > Gene Ontology > KEGG and Reactome Pathway |
Subcellular Location | Secreted. |
Domain |
PF10420 Cytokine interleukin-12p40 C-terminus |
Function |
Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. ; FUNCTION: Associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis. |
Biological Process |
GO:0001562 response to protozoan GO:0001787 natural killer cell proliferation GO:0001818 negative regulation of cytokine production GO:0001819 positive regulation of cytokine production GO:0001866 NK T cell proliferation GO:0001906 cell killing GO:0001909 leukocyte mediated cytotoxicity GO:0001910 regulation of leukocyte mediated cytotoxicity GO:0001912 positive regulation of leukocyte mediated cytotoxicity GO:0001913 T cell mediated cytotoxicity GO:0001914 regulation of T cell mediated cytotoxicity GO:0001916 positive regulation of T cell mediated cytotoxicity GO:0002228 natural killer cell mediated immunity GO:0002230 positive regulation of defense response to virus by host GO:0002237 response to molecule of bacterial origin GO:0002250 adaptive immune response GO:0002263 cell activation involved in immune response GO:0002285 lymphocyte activation involved in immune response GO:0002286 T cell activation involved in immune response GO:0002287 alpha-beta T cell activation involved in immune response GO:0002292 T cell differentiation involved in immune response GO:0002293 alpha-beta T cell differentiation involved in immune response GO:0002294 CD4-positive, alpha-beta T cell differentiation involved in immune response GO:0002295 T-helper cell lineage commitment GO:0002323 natural killer cell activation involved in immune response GO:0002347 response to tumor cell GO:0002360 T cell lineage commitment GO:0002363 alpha-beta T cell lineage commitment GO:0002366 leukocyte activation involved in immune response GO:0002418 immune response to tumor cell GO:0002420 natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002423 natural killer cell mediated immune response to tumor cell GO:0002437 inflammatory response to antigenic stimulus GO:0002443 leukocyte mediated immunity GO:0002449 lymphocyte mediated immunity GO:0002456 T cell mediated immunity GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002521 leukocyte differentiation GO:0002573 myeloid leukocyte differentiation GO:0002683 negative regulation of immune system process GO:0002694 regulation of leukocyte activation GO:0002696 positive regulation of leukocyte activation GO:0002697 regulation of immune effector process GO:0002699 positive regulation of immune effector process GO:0002703 regulation of leukocyte mediated immunity GO:0002705 positive regulation of leukocyte mediated immunity GO:0002706 regulation of lymphocyte mediated immunity GO:0002708 positive regulation of lymphocyte mediated immunity GO:0002709 regulation of T cell mediated immunity GO:0002711 positive regulation of T cell mediated immunity GO:0002715 regulation of natural killer cell mediated immunity GO:0002717 positive regulation of natural killer cell mediated immunity GO:0002761 regulation of myeloid leukocyte differentiation GO:0002763 positive regulation of myeloid leukocyte differentiation GO:0002819 regulation of adaptive immune response GO:0002821 positive regulation of adaptive immune response GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002825 regulation of T-helper 1 type immune response GO:0002827 positive regulation of T-helper 1 type immune response GO:0002831 regulation of response to biotic stimulus GO:0002833 positive regulation of response to biotic stimulus GO:0002834 regulation of response to tumor cell GO:0002836 positive regulation of response to tumor cell GO:0002837 regulation of immune response to tumor cell GO:0002839 positive regulation of immune response to tumor cell GO:0002855 regulation of natural killer cell mediated immune response to tumor cell GO:0002857 positive regulation of natural killer cell mediated immune response to tumor cell GO:0002858 regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002860 positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002861 regulation of inflammatory response to antigenic stimulus GO:0002862 negative regulation of inflammatory response to antigenic stimulus GO:0006606 protein import into nucleus GO:0006913 nucleocytoplasmic transport GO:0007050 cell cycle arrest GO:0007159 leukocyte cell-cell adhesion GO:0007249 I-kappaB kinase/NF-kappaB signaling GO:0007259 JAK-STAT cascade GO:0007260 tyrosine phosphorylation of STAT protein GO:0009314 response to radiation GO:0009411 response to UV GO:0009416 response to light stimulus GO:0009615 response to virus GO:0010224 response to UV-B GO:0010453 regulation of cell fate commitment GO:0010455 positive regulation of cell fate commitment GO:0010533 regulation of activation of Janus kinase activity GO:0010534 regulation of activation of JAK2 kinase activity GO:0010535 positive regulation of activation of JAK2 kinase activity GO:0010536 positive regulation of activation of Janus kinase activity GO:0010657 muscle cell apoptotic process GO:0010660 regulation of muscle cell apoptotic process GO:0010661 positive regulation of muscle cell apoptotic process GO:0017038 protein import GO:0018108 peptidyl-tyrosine phosphorylation GO:0018212 peptidyl-tyrosine modification GO:0019233 sensory perception of pain GO:0022407 regulation of cell-cell adhesion GO:0022409 positive regulation of cell-cell adhesion GO:0030098 lymphocyte differentiation GO:0030099 myeloid cell differentiation GO:0030101 natural killer cell activation GO:0030217 T cell differentiation GO:0030316 osteoclast differentiation GO:0031341 regulation of cell killing GO:0031343 positive regulation of cell killing GO:0031348 negative regulation of defense response GO:0031349 positive regulation of defense response GO:0031503 protein complex localization GO:0032102 negative regulation of response to external stimulus GO:0032103 positive regulation of response to external stimulus GO:0032147 activation of protein kinase activity GO:0032386 regulation of intracellular transport GO:0032388 positive regulation of intracellular transport GO:0032496 response to lipopolysaccharide GO:0032604 granulocyte macrophage colony-stimulating factor production GO:0032609 interferon-gamma production GO:0032613 interleukin-10 production GO:0032615 interleukin-12 production GO:0032620 interleukin-17 production GO:0032640 tumor necrosis factor production GO:0032645 regulation of granulocyte macrophage colony-stimulating factor production GO:0032649 regulation of interferon-gamma production GO:0032653 regulation of interleukin-10 production GO:0032655 regulation of interleukin-12 production GO:0032660 regulation of interleukin-17 production GO:0032680 regulation of tumor necrosis factor production GO:0032693 negative regulation of interleukin-10 production GO:0032700 negative regulation of interleukin-17 production GO:0032725 positive regulation of granulocyte macrophage colony-stimulating factor production GO:0032729 positive regulation of interferon-gamma production GO:0032733 positive regulation of interleukin-10 production GO:0032735 positive regulation of interleukin-12 production GO:0032740 positive regulation of interleukin-17 production GO:0032760 positive regulation of tumor necrosis factor production GO:0032814 regulation of natural killer cell activation GO:0032816 positive regulation of natural killer cell activation GO:0032817 regulation of natural killer cell proliferation GO:0032819 positive regulation of natural killer cell proliferation GO:0032943 mononuclear cell proliferation GO:0032944 regulation of mononuclear cell proliferation GO:0032946 positive regulation of mononuclear cell proliferation GO:0033002 muscle cell proliferation GO:0033157 regulation of intracellular protein transport GO:0033674 positive regulation of kinase activity GO:0034103 regulation of tissue remodeling GO:0034105 positive regulation of tissue remodeling GO:0034341 response to interferon-gamma GO:0034390 smooth muscle cell apoptotic process GO:0034391 regulation of smooth muscle cell apoptotic process GO:0034393 positive regulation of smooth muscle cell apoptotic process GO:0034504 protein localization to nucleus GO:0035710 CD4-positive, alpha-beta T cell activation GO:0042035 regulation of cytokine biosynthetic process GO:0042088 T-helper 1 type immune response GO:0042089 cytokine biosynthetic process GO:0042093 T-helper cell differentiation GO:0042095 interferon-gamma biosynthetic process GO:0042098 T cell proliferation GO:0042102 positive regulation of T cell proliferation GO:0042104 positive regulation of activated T cell proliferation GO:0042107 cytokine metabolic process GO:0042108 positive regulation of cytokine biosynthetic process GO:0042110 T cell activation GO:0042129 regulation of T cell proliferation GO:0042267 natural killer cell mediated cytotoxicity GO:0042269 regulation of natural killer cell mediated cytotoxicity GO:0042306 regulation of protein import into nucleus GO:0042307 positive regulation of protein import into nucleus GO:0042345 regulation of NF-kappaB import into nucleus GO:0042346 positive regulation of NF-kappaB import into nucleus GO:0042348 NF-kappaB import into nucleus GO:0042503 tyrosine phosphorylation of Stat3 protein GO:0042504 tyrosine phosphorylation of Stat4 protein GO:0042506 tyrosine phosphorylation of Stat5 protein GO:0042508 tyrosine phosphorylation of Stat1 protein GO:0042509 regulation of tyrosine phosphorylation of STAT protein GO:0042510 regulation of tyrosine phosphorylation of Stat1 protein GO:0042516 regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042519 regulation of tyrosine phosphorylation of Stat4 protein GO:0042520 positive regulation of tyrosine phosphorylation of Stat4 protein GO:0042522 regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein GO:0042742 defense response to bacterium GO:0042832 defense response to protozoan GO:0042976 activation of Janus kinase activity GO:0042977 activation of JAK2 kinase activity GO:0042990 regulation of transcription factor import into nucleus GO:0042991 transcription factor import into nucleus GO:0042993 positive regulation of transcription factor import into nucleus GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043367 CD4-positive, alpha-beta T cell differentiation GO:0043368 positive T cell selection GO:0043369 CD4-positive or CD8-positive, alpha-beta T cell lineage commitment GO:0043370 regulation of CD4-positive, alpha-beta T cell differentiation GO:0043372 positive regulation of CD4-positive, alpha-beta T cell differentiation GO:0043373 CD4-positive, alpha-beta T cell lineage commitment GO:0043379 memory T cell differentiation GO:0043380 regulation of memory T cell differentiation GO:0043382 positive regulation of memory T cell differentiation GO:0043900 regulation of multi-organism process GO:0043901 negative regulation of multi-organism process GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism GO:0044110 growth involved in symbiotic interaction GO:0044116 growth of symbiont involved in interaction with host GO:0044117 growth of symbiont in host GO:0044126 regulation of growth of symbiont in host GO:0044130 negative regulation of growth of symbiont in host GO:0044144 modulation of growth of symbiont involved in interaction with host GO:0044146 negative regulation of growth of symbiont involved in interaction with host GO:0044744 protein targeting to nucleus GO:0045058 T cell selection GO:0045072 regulation of interferon-gamma biosynthetic process GO:0045078 positive regulation of interferon-gamma biosynthetic process GO:0045088 regulation of innate immune response GO:0045089 positive regulation of innate immune response GO:0045165 cell fate commitment GO:0045580 regulation of T cell differentiation GO:0045582 positive regulation of T cell differentiation GO:0045619 regulation of lymphocyte differentiation GO:0045621 positive regulation of lymphocyte differentiation GO:0045622 regulation of T-helper cell differentiation GO:0045624 positive regulation of T-helper cell differentiation GO:0045637 regulation of myeloid cell differentiation GO:0045639 positive regulation of myeloid cell differentiation GO:0045670 regulation of osteoclast differentiation GO:0045672 positive regulation of osteoclast differentiation GO:0045785 positive regulation of cell adhesion GO:0045786 negative regulation of cell cycle GO:0045860 positive regulation of protein kinase activity GO:0045926 negative regulation of growth GO:0045954 positive regulation of natural killer cell mediated cytotoxicity GO:0046006 regulation of activated T cell proliferation GO:0046425 regulation of JAK-STAT cascade GO:0046427 positive regulation of JAK-STAT cascade GO:0046631 alpha-beta T cell activation GO:0046632 alpha-beta T cell differentiation GO:0046633 alpha-beta T cell proliferation GO:0046634 regulation of alpha-beta T cell activation GO:0046635 positive regulation of alpha-beta T cell activation GO:0046637 regulation of alpha-beta T cell differentiation GO:0046638 positive regulation of alpha-beta T cell differentiation GO:0046640 regulation of alpha-beta T cell proliferation GO:0046641 positive regulation of alpha-beta T cell proliferation GO:0046651 lymphocyte proliferation GO:0046822 regulation of nucleocytoplasmic transport GO:0046824 positive regulation of nucleocytoplasmic transport GO:0048659 smooth muscle cell proliferation GO:0048660 regulation of smooth muscle cell proliferation GO:0048662 negative regulation of smooth muscle cell proliferation GO:0048771 tissue remodeling GO:0050670 regulation of lymphocyte proliferation GO:0050671 positive regulation of lymphocyte proliferation GO:0050688 regulation of defense response to virus GO:0050691 regulation of defense response to virus by host GO:0050727 regulation of inflammatory response GO:0050728 negative regulation of inflammatory response GO:0050729 positive regulation of inflammatory response GO:0050730 regulation of peptidyl-tyrosine phosphorylation GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation GO:0050777 negative regulation of immune response GO:0050792 regulation of viral process GO:0050798 activated T cell proliferation GO:0050829 defense response to Gram-negative bacterium GO:0050863 regulation of T cell activation GO:0050865 regulation of cell activation GO:0050867 positive regulation of cell activation GO:0050870 positive regulation of T cell activation GO:0051132 NK T cell activation GO:0051133 regulation of NK T cell activation GO:0051135 positive regulation of NK T cell activation GO:0051140 regulation of NK T cell proliferation GO:0051142 positive regulation of NK T cell proliferation GO:0051169 nuclear transport GO:0051170 nuclear import GO:0051222 positive regulation of protein transport GO:0051249 regulation of lymphocyte activation GO:0051251 positive regulation of lymphocyte activation GO:0051607 defense response to virus GO:0070486 leukocyte aggregation GO:0070489 T cell aggregation GO:0070661 leukocyte proliferation GO:0070663 regulation of leukocyte proliferation GO:0070665 positive regulation of leukocyte proliferation GO:0071216 cellular response to biotic stimulus GO:0071219 cellular response to molecule of bacterial origin GO:0071222 cellular response to lipopolysaccharide GO:0071346 cellular response to interferon-gamma GO:0071396 cellular response to lipid GO:0071593 lymphocyte aggregation GO:0071706 tumor necrosis factor superfamily cytokine production GO:0072538 T-helper 17 type immune response GO:0072539 T-helper 17 cell differentiation GO:0072540 T-helper 17 cell lineage commitment GO:0090316 positive regulation of intracellular protein transport GO:0097696 STAT cascade GO:0098542 defense response to other organism GO:1900180 regulation of protein localization to nucleus GO:1900182 positive regulation of protein localization to nucleus GO:1902105 regulation of leukocyte differentiation GO:1902107 positive regulation of leukocyte differentiation GO:1902593 single-organism nuclear import GO:1903037 regulation of leukocyte cell-cell adhesion GO:1903039 positive regulation of leukocyte cell-cell adhesion GO:1903533 regulation of protein targeting GO:1903555 regulation of tumor necrosis factor superfamily cytokine production GO:1903557 positive regulation of tumor necrosis factor superfamily cytokine production GO:1903706 regulation of hemopoiesis GO:1903708 positive regulation of hemopoiesis GO:1903829 positive regulation of cellular protein localization GO:1904589 regulation of protein import GO:1904591 positive regulation of protein import GO:1904892 regulation of STAT cascade GO:1904894 positive regulation of STAT cascade GO:1904951 positive regulation of establishment of protein localization GO:2000316 regulation of T-helper 17 type immune response GO:2000318 positive regulation of T-helper 17 type immune response GO:2000319 regulation of T-helper 17 cell differentiation GO:2000321 positive regulation of T-helper 17 cell differentiation GO:2000328 regulation of T-helper 17 cell lineage commitment GO:2000330 positive regulation of T-helper 17 cell lineage commitment GO:2000514 regulation of CD4-positive, alpha-beta T cell activation GO:2000516 positive regulation of CD4-positive, alpha-beta T cell activation |
Molecular Function |
GO:0004896 cytokine receptor activity GO:0005125 cytokine activity GO:0005126 cytokine receptor binding GO:0005143 interleukin-12 receptor binding GO:0008083 growth factor activity GO:0019955 cytokine binding GO:0019972 interleukin-12 binding GO:0042164 interleukin-12 alpha subunit binding GO:0045519 interleukin-23 receptor binding GO:0046982 protein heterodimerization activity GO:0070851 growth factor receptor binding |
Cellular Component |
GO:0043514 interleukin-12 complex GO:0070743 interleukin-23 complex |
KEGG |
hsa04060 Cytokine-cytokine receptor interaction hsa04620 Toll-like receptor signaling pathway hsa04622 RIG-I-like receptor signaling pathway hsa04630 Jak-STAT signaling pathway |
Reactome |
R-HSA-1280215: Cytokine Signaling in Immune system R-HSA-168256: Immune System R-HSA-6783783: Interleukin-10 signaling R-HSA-447115: Interleukin-12 signaling R-HSA-6785807: Interleukin-4 and 13 signaling R-HSA-449147: Signaling by Interleukins |
Summary | |
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Symbol | IL12B |
Name | interleukin 12B |
Aliases | IL-12B; NKSF; CLMF2; natural killer cell stimulatory factor-2; cytotoxic lymphocyte maturation factor 2, p40 ...... |
Chromosomal Location | 5q33.3 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Content | Literatures that report relations between IL12B and anti-tumor immunity. The specific mechanism were also collected if the literature reports that a gene specifically promotes or inhibits the infiltration or function of T/NK cells. |
Literatures describing the relation between IL12B and anti-tumor immunity in human cancer.
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Summary | |
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Symbol | IL12B |
Name | interleukin 12B |
Aliases | IL-12B; NKSF; CLMF2; natural killer cell stimulatory factor-2; cytotoxic lymphocyte maturation factor 2, p40 ...... |
Chromosomal Location | 5q33.3 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Content | High-throughput screening data (e.g. CRISPR-Cas9, shRNA and RNAi) for T cell-mediated killing. Genetic screen techniques can identify mechanisms of tumor cell resistance (e.g., PTPN2) and sensitivity (e.g., APLNR) to killing by cytotoxic T cells, the central effectors of anti-tumor immunity. After comprehensively searching, eight groups of screening data sets were collected in the current database. In this tab, users can check whether their selected genes cause resistance or increase sensitivity to T cell-mediated killing in various data sets. |
> High-throughput Screening
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Statistical results of IL12B in screening data sets for detecting immune reponses.
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Summary | |
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Symbol | IL12B |
Name | interleukin 12B |
Aliases | IL-12B; NKSF; CLMF2; natural killer cell stimulatory factor-2; cytotoxic lymphocyte maturation factor 2, p40 ...... |
Chromosomal Location | 5q33.3 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Content |
Transcriptomic and genomic profiling of pre-treated tumor biopsies from responders and non-responders to immunotherapy. These data were used to identify signatures and mechanisms of response to checkpoint blockade (e.g., anti-PDL1 and anti-PD1). One example is that mutations in the gene PBRM1 benefit clinical survival of patients with clear cell renal cell carcinoma. After comprehensively searching, we collected 5 and 6 of transcriptomic and genomic data sets, respectively. In this tab, users can check whether their selected genes have significant difference of expression or mutation between responders and non-responders in various data sets. > Expression difference between responders and non-responders > Mutation difference between responders and non-responders |
Points in the above scatter plot represent the expression difference of IL12B in various data sets.
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Points in the above scatter plot represent the mutation difference of IL12B in various data sets.
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Summary | |
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Symbol | IL12B |
Name | interleukin 12B |
Aliases | IL-12B; NKSF; CLMF2; natural killer cell stimulatory factor-2; cytotoxic lymphocyte maturation factor 2, p40 ...... |
Chromosomal Location | 5q33.3 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Content |
Relations between abundance of tumor-infiltrating lymphocytes (TILs) and expression, copy number, methylation, or mutation of IL12B. The immune-related signatures of 28 TIL types from Charoentong's study, which can be viewed in the download page. For each cancer type, the relative abundance of TILs were inferred by using gene set variation analysis (GSVA) based on gene expression profile. In this tab, users can examine which kinds of TILs might be regulated by the current gene. |
Summary | |
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Symbol | IL12B |
Name | interleukin 12B |
Aliases | IL-12B; NKSF; CLMF2; natural killer cell stimulatory factor-2; cytotoxic lymphocyte maturation factor 2, p40 ...... |
Chromosomal Location | 5q33.3 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Content |
Relations between three kinds of immunomodulators and expression, copy number, methylation, or mutation of IL12B. These immunomo-dulators were collected from Charoentong's study. In this tab, users can examine which immunomodulators might be regulated by IL12B. > Immunoinhibitor > Immunostimulator > MHC molecule |
Summary | |
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Symbol | IL12B |
Name | interleukin 12B |
Aliases | IL-12B; NKSF; CLMF2; natural killer cell stimulatory factor-2; cytotoxic lymphocyte maturation factor 2, p40 ...... |
Chromosomal Location | 5q33.3 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Content |
Relations between chemokines (or receptors) and expression, copy number, methylation, or mutation of IL12B. In this tab, users can examine which chemokines (or receptors) might be regulated by the current gene. > Chemokine > Receptor |
Summary | |
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Symbol | IL12B |
Name | interleukin 12B |
Aliases | IL-12B; NKSF; CLMF2; natural killer cell stimulatory factor-2; cytotoxic lymphocyte maturation factor 2, p40 ...... |
Chromosomal Location | 5q33.3 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Content |
Distribution of IL12B expression across immune and molecular subtypes. > Immune subtype > Molecular subtype |
Summary | |
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Symbol | IL12B |
Name | interleukin 12B |
Aliases | IL-12B; NKSF; CLMF2; natural killer cell stimulatory factor-2; cytotoxic lymphocyte maturation factor 2, p40 ...... |
Chromosomal Location | 5q33.3 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Content |
Associations between IL12B and clinical features. > Overall survival analysis > Cancer stage > Tumor grade |
Summary | |
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Symbol | IL12B |
Name | interleukin 12B |
Aliases | IL-12B; NKSF; CLMF2; natural killer cell stimulatory factor-2; cytotoxic lymphocyte maturation factor 2, p40 ...... |
Chromosomal Location | 5q33.3 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Content | Drugs targeting IL12B collected from DrugBank database. |
Details on drugs targeting IL12B.
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