Summary | |
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Symbol | P2RX7 |
Name | purinergic receptor P2X, ligand gated ion channel, 7 |
Aliases | P2X7; MGC20089; purinergic receptor P2X, ligand-gated ion channel, 7; P2X7 receptor; P2Z receptor; purinergi ...... |
Chromosomal Location | 12q24 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Content |
Basic function annotation. > Subcellular Location, Domain and Function > Gene Ontology > KEGG and Reactome Pathway |
Subcellular Location | Cell membrane Multi-pass membrane protein |
Domain |
PF00864 ATP P2X receptor |
Function |
Receptor for ATP that acts as a ligand-gated ion channel. Responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells. In the absence of its natural ligand, ATP, functions as a scavenger receptor in the recognition and engulfment of apoptotic cells (PubMed:21821797, PubMed:23303206). |
Biological Process |
GO:0000187 activation of MAPK activity GO:0001501 skeletal system development GO:0001503 ossification GO:0001505 regulation of neurotransmitter levels GO:0001776 leukocyte homeostasis GO:0001819 positive regulation of cytokine production GO:0001845 phagolysosome assembly GO:0001894 tissue homeostasis GO:0001906 cell killing GO:0001909 leukocyte mediated cytotoxicity GO:0001910 regulation of leukocyte mediated cytotoxicity GO:0001912 positive regulation of leukocyte mediated cytotoxicity GO:0001913 T cell mediated cytotoxicity GO:0001914 regulation of T cell mediated cytotoxicity GO:0001916 positive regulation of T cell mediated cytotoxicity GO:0001933 negative regulation of protein phosphorylation GO:0002028 regulation of sodium ion transport GO:0002237 response to molecule of bacterial origin GO:0002250 adaptive immune response GO:0002260 lymphocyte homeostasis GO:0002443 leukocyte mediated immunity GO:0002449 lymphocyte mediated immunity GO:0002456 T cell mediated immunity GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002697 regulation of immune effector process GO:0002699 positive regulation of immune effector process GO:0002703 regulation of leukocyte mediated immunity GO:0002705 positive regulation of leukocyte mediated immunity GO:0002706 regulation of lymphocyte mediated immunity GO:0002708 positive regulation of lymphocyte mediated immunity GO:0002709 regulation of T cell mediated immunity GO:0002711 positive regulation of T cell mediated immunity GO:0002819 regulation of adaptive immune response GO:0002821 positive regulation of adaptive immune response GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0003254 regulation of membrane depolarization GO:0006090 pyruvate metabolic process GO:0006091 generation of precursor metabolites and energy GO:0006096 glycolytic process GO:0006109 regulation of carbohydrate metabolic process GO:0006110 regulation of glycolytic process GO:0006140 regulation of nucleotide metabolic process GO:0006165 nucleoside diphosphate phosphorylation GO:0006509 membrane protein ectodomain proteolysis GO:0006643 membrane lipid metabolic process GO:0006649 phospholipid transfer to membrane GO:0006665 sphingolipid metabolic process GO:0006672 ceramide metabolic process GO:0006732 coenzyme metabolic process GO:0006733 oxidoreduction coenzyme metabolic process GO:0006757 ATP generation from ADP GO:0006814 sodium ion transport GO:0006816 calcium ion transport GO:0006820 anion transport GO:0006835 dicarboxylic acid transport GO:0006836 neurotransmitter transport GO:0006862 nucleotide transport GO:0006869 lipid transport GO:0006874 cellular calcium ion homeostasis GO:0006875 cellular metal ion homeostasis GO:0006884 cell volume homeostasis GO:0006887 exocytosis GO:0006900 membrane budding GO:0006909 phagocytosis GO:0007009 plasma membrane organization GO:0007033 vacuole organization GO:0007040 lysosome organization GO:0007159 leukocyte cell-cell adhesion GO:0007204 positive regulation of cytosolic calcium ion concentration GO:0007269 neurotransmitter secretion GO:0007586 digestion GO:0007596 blood coagulation GO:0007599 hemostasis GO:0008361 regulation of cell size GO:0009116 nucleoside metabolic process GO:0009118 regulation of nucleoside metabolic process GO:0009119 ribonucleoside metabolic process GO:0009123 nucleoside monophosphate metabolic process GO:0009126 purine nucleoside monophosphate metabolic process GO:0009132 nucleoside diphosphate metabolic process GO:0009135 purine nucleoside diphosphate metabolic process GO:0009141 nucleoside triphosphate metabolic process GO:0009144 purine nucleoside triphosphate metabolic process GO:0009150 purine ribonucleotide metabolic process GO:0009161 ribonucleoside monophosphate metabolic process GO:0009167 purine ribonucleoside monophosphate metabolic process GO:0009179 purine ribonucleoside diphosphate metabolic process GO:0009185 ribonucleoside diphosphate metabolic process GO:0009199 ribonucleoside triphosphate metabolic process GO:0009205 purine ribonucleoside triphosphate metabolic process GO:0009306 protein secretion GO:0009612 response to mechanical stimulus GO:0009894 regulation of catabolic process GO:0009896 positive regulation of catabolic process GO:0009991 response to extracellular stimulus GO:0010035 response to inorganic substance GO:0010038 response to metal ion GO:0010043 response to zinc ion GO:0010522 regulation of calcium ion transport into cytosol GO:0010524 positive regulation of calcium ion transport into cytosol GO:0010876 lipid localization GO:0010959 regulation of metal ion transport GO:0014047 glutamate secretion GO:0014048 regulation of glutamate secretion GO:0014049 positive regulation of glutamate secretion GO:0014051 gamma-aminobutyric acid secretion GO:0014052 regulation of gamma-aminobutyric acid secretion GO:0014054 positive regulation of gamma-aminobutyric acid secretion GO:0014074 response to purine-containing compound GO:0015672 monovalent inorganic cation transport GO:0015711 organic anion transport GO:0015718 monocarboxylic acid transport GO:0015732 prostaglandin transport GO:0015748 organophosphate ester transport GO:0015812 gamma-aminobutyric acid transport GO:0015908 fatty acid transport GO:0015914 phospholipid transport GO:0015931 nucleobase-containing compound transport GO:0016050 vesicle organization GO:0016052 carbohydrate catabolic process GO:0016079 synaptic vesicle exocytosis GO:0016485 protein processing GO:0017121 phospholipid scrambling GO:0017156 calcium ion regulated exocytosis GO:0019233 sensory perception of pain GO:0019362 pyridine nucleotide metabolic process GO:0019835 cytolysis GO:0023061 signal release GO:0030031 cell projection assembly GO:0030148 sphingolipid biosynthetic process GO:0030278 regulation of ossification GO:0030282 bone mineralization GO:0030500 regulation of bone mineralization GO:0030501 positive regulation of bone mineralization GO:0031214 biomineral tissue development GO:0031329 regulation of cellular catabolic process GO:0031331 positive regulation of cellular catabolic process GO:0031341 regulation of cell killing GO:0031343 positive regulation of cell killing GO:0031346 positive regulation of cell projection organization GO:0031640 killing of cells of other organism GO:0031668 cellular response to extracellular stimulus GO:0032060 bleb assembly GO:0032147 activation of protein kinase activity GO:0032303 regulation of icosanoid secretion GO:0032305 positive regulation of icosanoid secretion GO:0032306 regulation of prostaglandin secretion GO:0032308 positive regulation of prostaglandin secretion GO:0032309 icosanoid secretion GO:0032310 prostaglandin secretion GO:0032368 regulation of lipid transport GO:0032370 positive regulation of lipid transport GO:0032496 response to lipopolysaccharide GO:0032535 regulation of cellular component size GO:0032610 interleukin-1 alpha production GO:0032611 interleukin-1 beta production GO:0032612 interleukin-1 production GO:0032635 interleukin-6 production GO:0032650 regulation of interleukin-1 alpha production GO:0032651 regulation of interleukin-1 beta production GO:0032652 regulation of interleukin-1 production GO:0032675 regulation of interleukin-6 production GO:0032730 positive regulation of interleukin-1 alpha production GO:0032731 positive regulation of interleukin-1 beta production GO:0032732 positive regulation of interleukin-1 production GO:0032755 positive regulation of interleukin-6 production GO:0032844 regulation of homeostatic process GO:0032845 negative regulation of homeostatic process GO:0032846 positive regulation of homeostatic process GO:0032943 mononuclear cell proliferation GO:0032963 collagen metabolic process GO:0033198 response to ATP GO:0033619 membrane protein proteolysis GO:0033674 positive regulation of kinase activity GO:0034103 regulation of tissue remodeling GO:0034104 negative regulation of tissue remodeling GO:0034204 lipid translocation GO:0034405 response to fluid shear stress GO:0034762 regulation of transmembrane transport GO:0034764 positive regulation of transmembrane transport GO:0034765 regulation of ion transmembrane transport GO:0034767 positive regulation of ion transmembrane transport GO:0035587 purinergic receptor signaling pathway GO:0035590 purinergic nucleotide receptor signaling pathway GO:0035821 modification of morphology or physiology of other organism GO:0042098 T cell proliferation GO:0042110 T cell activation GO:0042268 regulation of cytolysis GO:0042278 purine nucleoside metabolic process GO:0042326 negative regulation of phosphorylation GO:0042391 regulation of membrane potential GO:0042493 response to drug GO:0042742 defense response to bacterium GO:0043029 T cell homeostasis GO:0043132 NAD transport GO:0043270 positive regulation of ion transport GO:0043331 response to dsRNA GO:0043405 regulation of MAP kinase activity GO:0043406 positive regulation of MAP kinase activity GO:0043409 negative regulation of MAPK cascade GO:0043410 positive regulation of MAPK cascade GO:0043467 regulation of generation of precursor metabolites and energy GO:0043470 regulation of carbohydrate catabolic process GO:0043900 regulation of multi-organism process GO:0044070 regulation of anion transport GO:0044089 positive regulation of cellular component biogenesis GO:0044236 multicellular organism metabolic process GO:0044243 multicellular organism catabolic process GO:0044254 multicellular organismal protein catabolic process GO:0044256 protein digestion GO:0044259 multicellular organismal macromolecule metabolic process GO:0044266 multicellular organismal macromolecule catabolic process GO:0044268 multicellular organismal protein metabolic process GO:0044364 disruption of cells of other organism GO:0044723 single-organism carbohydrate metabolic process GO:0044724 single-organism carbohydrate catabolic process GO:0045055 regulated exocytosis GO:0045124 regulation of bone resorption GO:0045332 phospholipid translocation GO:0045453 bone resorption GO:0045778 positive regulation of ossification GO:0045779 negative regulation of bone resorption GO:0045794 negative regulation of cell volume GO:0045821 positive regulation of glycolytic process GO:0045860 positive regulation of protein kinase activity GO:0045913 positive regulation of carbohydrate metabolic process GO:0045919 positive regulation of cytolysis GO:0045979 positive regulation of nucleoside metabolic process GO:0045981 positive regulation of nucleotide metabolic process GO:0046031 ADP metabolic process GO:0046034 ATP metabolic process GO:0046128 purine ribonucleoside metabolic process GO:0046467 membrane lipid biosynthetic process GO:0046496 nicotinamide nucleotide metabolic process GO:0046513 ceramide biosynthetic process GO:0046651 lymphocyte proliferation GO:0046683 response to organophosphorus GO:0046717 acid secretion GO:0046849 bone remodeling GO:0046850 regulation of bone remodeling GO:0046851 negative regulation of bone remodeling GO:0046931 pore complex assembly GO:0046939 nucleotide phosphorylation GO:0046942 carboxylic acid transport GO:0048489 synaptic vesicle transport GO:0048705 skeletal system morphogenesis GO:0048771 tissue remodeling GO:0048871 multicellular organismal homeostasis GO:0048872 homeostasis of number of cells GO:0048873 homeostasis of number of cells within a tissue GO:0050663 cytokine secretion GO:0050701 interleukin-1 secretion GO:0050702 interleukin-1 beta secretion GO:0050703 interleukin-1 alpha secretion GO:0050704 regulation of interleukin-1 secretion GO:0050705 regulation of interleukin-1 alpha secretion GO:0050706 regulation of interleukin-1 beta secretion GO:0050707 regulation of cytokine secretion GO:0050708 regulation of protein secretion GO:0050714 positive regulation of protein secretion GO:0050715 positive regulation of cytokine secretion GO:0050716 positive regulation of interleukin-1 secretion GO:0050717 positive regulation of interleukin-1 alpha secretion GO:0050718 positive regulation of interleukin-1 beta secretion GO:0050817 coagulation GO:0050830 defense response to Gram-positive bacterium GO:0050878 regulation of body fluid levels GO:0051047 positive regulation of secretion GO:0051181 cofactor transport GO:0051186 cofactor metabolic process GO:0051193 regulation of cofactor metabolic process GO:0051194 positive regulation of cofactor metabolic process GO:0051196 regulation of coenzyme metabolic process GO:0051197 positive regulation of coenzyme metabolic process GO:0051208 sequestering of calcium ion GO:0051209 release of sequestered calcium ion into cytosol GO:0051222 positive regulation of protein transport GO:0051235 maintenance of location GO:0051238 sequestering of metal ion GO:0051259 protein oligomerization GO:0051282 regulation of sequestering of calcium ion GO:0051283 negative regulation of sequestering of calcium ion GO:0051480 regulation of cytosolic calcium ion concentration GO:0051493 regulation of cytoskeleton organization GO:0051495 positive regulation of cytoskeleton organization GO:0051592 response to calcium ion GO:0051602 response to electrical stimulus GO:0051604 protein maturation GO:0051640 organelle localization GO:0051648 vesicle localization GO:0051650 establishment of vesicle localization GO:0051656 establishment of organelle localization GO:0051709 regulation of killing of cells of other organism GO:0051881 regulation of mitochondrial membrane potential GO:0051882 mitochondrial depolarization GO:0051899 membrane depolarization GO:0051900 regulation of mitochondrial depolarization GO:0051901 positive regulation of mitochondrial depolarization GO:0051924 regulation of calcium ion transport GO:0051928 positive regulation of calcium ion transport GO:0055074 calcium ion homeostasis GO:0060249 anatomical structure homeostasis GO:0060401 cytosolic calcium ion transport GO:0060402 calcium ion transport into cytosol GO:0060491 regulation of cell projection assembly GO:0070167 regulation of biomineral tissue development GO:0070169 positive regulation of biomineral tissue development GO:0070227 lymphocyte apoptotic process GO:0070228 regulation of lymphocyte apoptotic process GO:0070230 positive regulation of lymphocyte apoptotic process GO:0070486 leukocyte aggregation GO:0070489 T cell aggregation GO:0070509 calcium ion import GO:0070588 calcium ion transmembrane transport GO:0070661 leukocyte proliferation GO:0070838 divalent metal ion transport GO:0071359 cellular response to dsRNA GO:0071407 cellular response to organic cyclic compound GO:0071496 cellular response to external stimulus GO:0071593 lymphocyte aggregation GO:0071715 icosanoid transport GO:0071887 leukocyte apoptotic process GO:0071900 regulation of protein serine/threonine kinase activity GO:0071902 positive regulation of protein serine/threonine kinase activity GO:0072503 cellular divalent inorganic cation homeostasis GO:0072507 divalent inorganic cation homeostasis GO:0072511 divalent inorganic cation transport GO:0072524 pyridine-containing compound metabolic process GO:0072593 reactive oxygen species metabolic process GO:0080171 lytic vacuole organization GO:0090066 regulation of anatomical structure size GO:0090382 phagosome maturation GO:0097035 regulation of membrane lipid distribution GO:0097191 extrinsic apoptotic signaling pathway GO:0097479 synaptic vesicle localization GO:0097480 establishment of synaptic vesicle localization GO:0097553 calcium ion transmembrane import into cytosol GO:0098542 defense response to other organism GO:0099003 vesicle-mediated transport in synapse GO:0099504 synaptic vesicle cycle GO:0099531 presynaptic process involved in chemical synaptic transmission GO:0099643 signal release from synapse GO:1900542 regulation of purine nucleotide metabolic process GO:1900544 positive regulation of purine nucleotide metabolic process GO:1901657 glycosyl compound metabolic process GO:1902532 negative regulation of intracellular signal transduction GO:1902656 calcium ion import into cytosol GO:1903532 positive regulation of secretion by cell GO:1903578 regulation of ATP metabolic process GO:1903580 positive regulation of ATP metabolic process GO:1903793 positive regulation of anion transport GO:1904170 regulation of bleb assembly GO:1904172 positive regulation of bleb assembly GO:1904181 positive regulation of membrane depolarization GO:1904951 positive regulation of establishment of protein localization GO:1990267 response to transition metal nanoparticle GO:2000021 regulation of ion homeostasis GO:2000106 regulation of leukocyte apoptotic process GO:2000108 positive regulation of leukocyte apoptotic process GO:2000191 regulation of fatty acid transport GO:2000193 positive regulation of fatty acid transport |
Molecular Function |
GO:0001530 lipopolysaccharide binding GO:0001614 purinergic nucleotide receptor activity GO:0004931 extracellular ATP-gated cation channel activity GO:0005216 ion channel activity GO:0005230 extracellular ligand-gated ion channel activity GO:0005231 excitatory extracellular ligand-gated ion channel activity GO:0005261 cation channel activity GO:0015267 channel activity GO:0015276 ligand-gated ion channel activity GO:0016502 nucleotide receptor activity GO:0022803 passive transmembrane transporter activity GO:0022834 ligand-gated channel activity GO:0022836 gated channel activity GO:0022838 substrate-specific channel activity GO:0035381 ATP-gated ion channel activity GO:0035586 purinergic receptor activity |
Cellular Component |
GO:0005635 nuclear envelope GO:0005637 nuclear inner membrane GO:0005639 integral component of nuclear inner membrane GO:0009897 external side of plasma membrane GO:0031229 intrinsic component of nuclear inner membrane GO:0031300 intrinsic component of organelle membrane GO:0031301 integral component of organelle membrane GO:0031594 neuromuscular junction GO:0031965 nuclear membrane GO:0032059 bleb GO:0043025 neuronal cell body GO:0044297 cell body GO:0044453 nuclear membrane part GO:0098552 side of membrane GO:0098793 presynapse |
KEGG |
hsa04020 Calcium signaling pathway hsa04080 Neuroactive ligand-receptor interaction hsa04621 NOD-like receptor signaling pathway |
Reactome |
R-HSA-139853: Elevation of cytosolic Ca2+ levels R-HSA-109582: Hemostasis R-HSA-168256: Immune System R-HSA-622312: Inflammasomes R-HSA-168249: Innate Immune System R-HSA-168643: Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-418360: Platelet calcium homeostasis R-HSA-418346: Platelet homeostasis R-HSA-844456: The NLRP3 inflammasome |
Summary | |
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Symbol | P2RX7 |
Name | purinergic receptor P2X, ligand gated ion channel, 7 |
Aliases | P2X7; MGC20089; purinergic receptor P2X, ligand-gated ion channel, 7; P2X7 receptor; P2Z receptor; purinergi ...... |
Chromosomal Location | 12q24 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Content | Literatures that report relations between P2RX7 and anti-tumor immunity. The specific mechanism were also collected if the literature reports that a gene specifically promotes or inhibits the infiltration or function of T/NK cells. |
Literatures describing the relation between P2RX7 and anti-tumor immunity in human cancer.
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Summary | |
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Symbol | P2RX7 |
Name | purinergic receptor P2X, ligand gated ion channel, 7 |
Aliases | P2X7; MGC20089; purinergic receptor P2X, ligand-gated ion channel, 7; P2X7 receptor; P2Z receptor; purinergi ...... |
Chromosomal Location | 12q24 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Content | High-throughput screening data (e.g. CRISPR-Cas9, shRNA and RNAi) for T cell-mediated killing. Genetic screen techniques can identify mechanisms of tumor cell resistance (e.g., PTPN2) and sensitivity (e.g., APLNR) to killing by cytotoxic T cells, the central effectors of anti-tumor immunity. After comprehensively searching, eight groups of screening data sets were collected in the current database. In this tab, users can check whether their selected genes cause resistance or increase sensitivity to T cell-mediated killing in various data sets. |
> High-throughput Screening
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Statistical results of P2RX7 in screening data sets for detecting immune reponses.
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Summary | |
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Symbol | P2RX7 |
Name | purinergic receptor P2X, ligand gated ion channel, 7 |
Aliases | P2X7; MGC20089; purinergic receptor P2X, ligand-gated ion channel, 7; P2X7 receptor; P2Z receptor; purinergi ...... |
Chromosomal Location | 12q24 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Content |
Transcriptomic and genomic profiling of pre-treated tumor biopsies from responders and non-responders to immunotherapy. These data were used to identify signatures and mechanisms of response to checkpoint blockade (e.g., anti-PDL1 and anti-PD1). One example is that mutations in the gene PBRM1 benefit clinical survival of patients with clear cell renal cell carcinoma. After comprehensively searching, we collected 5 and 6 of transcriptomic and genomic data sets, respectively. In this tab, users can check whether their selected genes have significant difference of expression or mutation between responders and non-responders in various data sets. > Expression difference between responders and non-responders > Mutation difference between responders and non-responders |
Points in the above scatter plot represent the expression difference of P2RX7 in various data sets.
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Points in the above scatter plot represent the mutation difference of P2RX7 in various data sets.
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Summary | |
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Symbol | P2RX7 |
Name | purinergic receptor P2X, ligand gated ion channel, 7 |
Aliases | P2X7; MGC20089; purinergic receptor P2X, ligand-gated ion channel, 7; P2X7 receptor; P2Z receptor; purinergi ...... |
Chromosomal Location | 12q24 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Content |
Relations between abundance of tumor-infiltrating lymphocytes (TILs) and expression, copy number, methylation, or mutation of P2RX7. The immune-related signatures of 28 TIL types from Charoentong's study, which can be viewed in the download page. For each cancer type, the relative abundance of TILs were inferred by using gene set variation analysis (GSVA) based on gene expression profile. In this tab, users can examine which kinds of TILs might be regulated by the current gene. |
Summary | |
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Symbol | P2RX7 |
Name | purinergic receptor P2X, ligand gated ion channel, 7 |
Aliases | P2X7; MGC20089; purinergic receptor P2X, ligand-gated ion channel, 7; P2X7 receptor; P2Z receptor; purinergi ...... |
Chromosomal Location | 12q24 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Content |
Relations between three kinds of immunomodulators and expression, copy number, methylation, or mutation of P2RX7. These immunomo-dulators were collected from Charoentong's study. In this tab, users can examine which immunomodulators might be regulated by P2RX7. > Immunoinhibitor > Immunostimulator > MHC molecule |
Summary | |
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Symbol | P2RX7 |
Name | purinergic receptor P2X, ligand gated ion channel, 7 |
Aliases | P2X7; MGC20089; purinergic receptor P2X, ligand-gated ion channel, 7; P2X7 receptor; P2Z receptor; purinergi ...... |
Chromosomal Location | 12q24 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Content |
Relations between chemokines (or receptors) and expression, copy number, methylation, or mutation of P2RX7. In this tab, users can examine which chemokines (or receptors) might be regulated by the current gene. > Chemokine > Receptor |
Summary | |
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Symbol | P2RX7 |
Name | purinergic receptor P2X, ligand gated ion channel, 7 |
Aliases | P2X7; MGC20089; purinergic receptor P2X, ligand-gated ion channel, 7; P2X7 receptor; P2Z receptor; purinergi ...... |
Chromosomal Location | 12q24 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Content |
Distribution of P2RX7 expression across immune and molecular subtypes. > Immune subtype > Molecular subtype |
Summary | |
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Symbol | P2RX7 |
Name | purinergic receptor P2X, ligand gated ion channel, 7 |
Aliases | P2X7; MGC20089; purinergic receptor P2X, ligand-gated ion channel, 7; P2X7 receptor; P2Z receptor; purinergi ...... |
Chromosomal Location | 12q24 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Content |
Associations between P2RX7 and clinical features. > Overall survival analysis > Cancer stage > Tumor grade |
Summary | |
---|---|
Symbol | P2RX7 |
Name | purinergic receptor P2X, ligand gated ion channel, 7 |
Aliases | P2X7; MGC20089; purinergic receptor P2X, ligand-gated ion channel, 7; P2X7 receptor; P2Z receptor; purinergi ...... |
Chromosomal Location | 12q24 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Content | Drugs targeting P2RX7 collected from DrugBank database. |
There is no record. |