Summary | |
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Symbol | RSL24D1 |
Name | ribosomal L24 domain containing 1 |
Aliases | HRP-L30-iso; RPL24L; C15orf15; chromosome 15 open reading frame 15; RLP24; TVAS3; 60S ribosomal protein L30 ...... |
Chromosomal Location | 15q21 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Content |
Basic function annotation. > Subcellular Location, Domain and Function > Gene Ontology > KEGG and Reactome Pathway |
Subcellular Location | Nucleus, nucleolus |
Domain |
PF01246 Ribosomal protein L24e |
Function |
Involved in the biogenesis of the 60S ribosomal subunit. Ensures the docking of GTPBP4/NOG1 to pre-60S particles (By similarity). |
Biological Process |
GO:0000027 ribosomal large subunit assembly GO:0022613 ribonucleoprotein complex biogenesis GO:0022618 ribonucleoprotein complex assembly GO:0042254 ribosome biogenesis GO:0042255 ribosome assembly GO:0042273 ribosomal large subunit biogenesis GO:0071826 ribonucleoprotein complex subunit organization GO:1902626 assembly of large subunit precursor of preribosome |
Molecular Function |
GO:0003735 structural constituent of ribosome |
Cellular Component |
GO:0005840 ribosome GO:0015934 large ribosomal subunit GO:0022625 cytosolic large ribosomal subunit GO:0022626 cytosolic ribosome GO:0044391 ribosomal subunit GO:0044445 cytosolic part |
KEGG |
hsa03010 Ribosome |
Reactome | - |
Summary | |
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Symbol | RSL24D1 |
Name | ribosomal L24 domain containing 1 |
Aliases | HRP-L30-iso; RPL24L; C15orf15; chromosome 15 open reading frame 15; RLP24; TVAS3; 60S ribosomal protein L30 ...... |
Chromosomal Location | 15q21 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Content | Literatures that report relations between RSL24D1 and anti-tumor immunity. The specific mechanism were also collected if the literature reports that a gene specifically promotes or inhibits the infiltration or function of T/NK cells. |
There is no record. |
Summary | |
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Symbol | RSL24D1 |
Name | ribosomal L24 domain containing 1 |
Aliases | HRP-L30-iso; RPL24L; C15orf15; chromosome 15 open reading frame 15; RLP24; TVAS3; 60S ribosomal protein L30 ...... |
Chromosomal Location | 15q21 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Content | High-throughput screening data (e.g. CRISPR-Cas9, shRNA and RNAi) for T cell-mediated killing. Genetic screen techniques can identify mechanisms of tumor cell resistance (e.g., PTPN2) and sensitivity (e.g., APLNR) to killing by cytotoxic T cells, the central effectors of anti-tumor immunity. After comprehensively searching, eight groups of screening data sets were collected in the current database. In this tab, users can check whether their selected genes cause resistance or increase sensitivity to T cell-mediated killing in various data sets. |
> High-throughput Screening
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Statistical results of RSL24D1 in screening data sets for detecting immune reponses.
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Summary | |
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Symbol | RSL24D1 |
Name | ribosomal L24 domain containing 1 |
Aliases | HRP-L30-iso; RPL24L; C15orf15; chromosome 15 open reading frame 15; RLP24; TVAS3; 60S ribosomal protein L30 ...... |
Chromosomal Location | 15q21 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Content |
Transcriptomic and genomic profiling of pre-treated tumor biopsies from responders and non-responders to immunotherapy. These data were used to identify signatures and mechanisms of response to checkpoint blockade (e.g., anti-PDL1 and anti-PD1). One example is that mutations in the gene PBRM1 benefit clinical survival of patients with clear cell renal cell carcinoma. After comprehensively searching, we collected 5 and 6 of transcriptomic and genomic data sets, respectively. In this tab, users can check whether their selected genes have significant difference of expression or mutation between responders and non-responders in various data sets. > Expression difference between responders and non-responders > Mutation difference between responders and non-responders |
Points in the above scatter plot represent the expression difference of RSL24D1 in various data sets.
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Points in the above scatter plot represent the mutation difference of RSL24D1 in various data sets.
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Summary | |
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Symbol | RSL24D1 |
Name | ribosomal L24 domain containing 1 |
Aliases | HRP-L30-iso; RPL24L; C15orf15; chromosome 15 open reading frame 15; RLP24; TVAS3; 60S ribosomal protein L30 ...... |
Chromosomal Location | 15q21 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Content |
Relations between abundance of tumor-infiltrating lymphocytes (TILs) and expression, copy number, methylation, or mutation of RSL24D1. The immune-related signatures of 28 TIL types from Charoentong's study, which can be viewed in the download page. For each cancer type, the relative abundance of TILs were inferred by using gene set variation analysis (GSVA) based on gene expression profile. In this tab, users can examine which kinds of TILs might be regulated by the current gene. |
Summary | |
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Symbol | RSL24D1 |
Name | ribosomal L24 domain containing 1 |
Aliases | HRP-L30-iso; RPL24L; C15orf15; chromosome 15 open reading frame 15; RLP24; TVAS3; 60S ribosomal protein L30 ...... |
Chromosomal Location | 15q21 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Content |
Relations between three kinds of immunomodulators and expression, copy number, methylation, or mutation of RSL24D1. These immunomo-dulators were collected from Charoentong's study. In this tab, users can examine which immunomodulators might be regulated by RSL24D1. > Immunoinhibitor > Immunostimulator > MHC molecule |
Summary | |
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Symbol | RSL24D1 |
Name | ribosomal L24 domain containing 1 |
Aliases | HRP-L30-iso; RPL24L; C15orf15; chromosome 15 open reading frame 15; RLP24; TVAS3; 60S ribosomal protein L30 ...... |
Chromosomal Location | 15q21 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Content |
Relations between chemokines (or receptors) and expression, copy number, methylation, or mutation of RSL24D1. In this tab, users can examine which chemokines (or receptors) might be regulated by the current gene. > Chemokine > Receptor |
Summary | |
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Symbol | RSL24D1 |
Name | ribosomal L24 domain containing 1 |
Aliases | HRP-L30-iso; RPL24L; C15orf15; chromosome 15 open reading frame 15; RLP24; TVAS3; 60S ribosomal protein L30 ...... |
Chromosomal Location | 15q21 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Content |
Distribution of RSL24D1 expression across immune and molecular subtypes. > Immune subtype > Molecular subtype |
Summary | |
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Symbol | RSL24D1 |
Name | ribosomal L24 domain containing 1 |
Aliases | HRP-L30-iso; RPL24L; C15orf15; chromosome 15 open reading frame 15; RLP24; TVAS3; 60S ribosomal protein L30 ...... |
Chromosomal Location | 15q21 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Content |
Associations between RSL24D1 and clinical features. > Overall survival analysis > Cancer stage > Tumor grade |
Summary | |
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Symbol | RSL24D1 |
Name | ribosomal L24 domain containing 1 |
Aliases | HRP-L30-iso; RPL24L; C15orf15; chromosome 15 open reading frame 15; RLP24; TVAS3; 60S ribosomal protein L30 ...... |
Chromosomal Location | 15q21 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Content | Drugs targeting RSL24D1 collected from DrugBank database. |
Details on drugs targeting RSL24D1.
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