Summary | |
---|---|
Symbol | YIF1B |
Name | Yip1 interacting factor homolog B (S. cerevisiae) |
Aliases | FinGER8; YIP1-interacting factor homolog B; Protein YIF1B |
Chromosomal Location | 19q13.2 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Content |
Basic function annotation. > Subcellular Location, Domain and Function > Gene Ontology > KEGG and Reactome Pathway |
Subcellular Location | Membrane Multi-pass membrane protein |
Domain |
PF03878 YIF1 |
Function |
- |
Biological Process |
GO:0006888 ER to Golgi vesicle-mediated transport GO:0048193 Golgi vesicle transport |
Molecular Function | - |
Cellular Component |
GO:0005793 endoplasmic reticulum-Golgi intermediate compartment GO:0030133 transport vesicle GO:0030134 ER to Golgi transport vesicle GO:0030135 coated vesicle GO:0030173 integral component of Golgi membrane GO:0031228 intrinsic component of Golgi membrane GO:0031300 intrinsic component of organelle membrane GO:0031301 integral component of organelle membrane |
KEGG | - |
Reactome | - |
Summary | |
---|---|
Symbol | YIF1B |
Name | Yip1 interacting factor homolog B (S. cerevisiae) |
Aliases | FinGER8; YIP1-interacting factor homolog B; Protein YIF1B |
Chromosomal Location | 19q13.2 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Content | Literatures that report relations between YIF1B and anti-tumor immunity. The specific mechanism were also collected if the literature reports that a gene specifically promotes or inhibits the infiltration or function of T/NK cells. |
There is no record. |
Summary | |
---|---|
Symbol | YIF1B |
Name | Yip1 interacting factor homolog B (S. cerevisiae) |
Aliases | FinGER8; YIP1-interacting factor homolog B; Protein YIF1B |
Chromosomal Location | 19q13.2 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Content | High-throughput screening data (e.g. CRISPR-Cas9, shRNA and RNAi) for T cell-mediated killing. Genetic screen techniques can identify mechanisms of tumor cell resistance (e.g., PTPN2) and sensitivity (e.g., APLNR) to killing by cytotoxic T cells, the central effectors of anti-tumor immunity. After comprehensively searching, eight groups of screening data sets were collected in the current database. In this tab, users can check whether their selected genes cause resistance or increase sensitivity to T cell-mediated killing in various data sets. |
> High-throughput Screening
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Statistical results of YIF1B in screening data sets for detecting immune reponses.
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Summary | |
---|---|
Symbol | YIF1B |
Name | Yip1 interacting factor homolog B (S. cerevisiae) |
Aliases | FinGER8; YIP1-interacting factor homolog B; Protein YIF1B |
Chromosomal Location | 19q13.2 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Content |
Transcriptomic and genomic profiling of pre-treated tumor biopsies from responders and non-responders to immunotherapy. These data were used to identify signatures and mechanisms of response to checkpoint blockade (e.g., anti-PDL1 and anti-PD1). One example is that mutations in the gene PBRM1 benefit clinical survival of patients with clear cell renal cell carcinoma. After comprehensively searching, we collected 5 and 6 of transcriptomic and genomic data sets, respectively. In this tab, users can check whether their selected genes have significant difference of expression or mutation between responders and non-responders in various data sets. > Expression difference between responders and non-responders > Mutation difference between responders and non-responders |
Points in the above scatter plot represent the expression difference of YIF1B in various data sets.
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Points in the above scatter plot represent the mutation difference of YIF1B in various data sets.
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Summary | |
---|---|
Symbol | YIF1B |
Name | Yip1 interacting factor homolog B (S. cerevisiae) |
Aliases | FinGER8; YIP1-interacting factor homolog B; Protein YIF1B |
Chromosomal Location | 19q13.2 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Content |
Relations between abundance of tumor-infiltrating lymphocytes (TILs) and expression, copy number, methylation, or mutation of YIF1B. The immune-related signatures of 28 TIL types from Charoentong's study, which can be viewed in the download page. For each cancer type, the relative abundance of TILs were inferred by using gene set variation analysis (GSVA) based on gene expression profile. In this tab, users can examine which kinds of TILs might be regulated by the current gene. |
Summary | |
---|---|
Symbol | YIF1B |
Name | Yip1 interacting factor homolog B (S. cerevisiae) |
Aliases | FinGER8; YIP1-interacting factor homolog B; Protein YIF1B |
Chromosomal Location | 19q13.2 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Content |
Relations between three kinds of immunomodulators and expression, copy number, methylation, or mutation of YIF1B. These immunomo-dulators were collected from Charoentong's study. In this tab, users can examine which immunomodulators might be regulated by YIF1B. > Immunoinhibitor > Immunostimulator > MHC molecule |
Summary | |
---|---|
Symbol | YIF1B |
Name | Yip1 interacting factor homolog B (S. cerevisiae) |
Aliases | FinGER8; YIP1-interacting factor homolog B; Protein YIF1B |
Chromosomal Location | 19q13.2 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Content |
Relations between chemokines (or receptors) and expression, copy number, methylation, or mutation of YIF1B. In this tab, users can examine which chemokines (or receptors) might be regulated by the current gene. > Chemokine > Receptor |
Summary | |
---|---|
Symbol | YIF1B |
Name | Yip1 interacting factor homolog B (S. cerevisiae) |
Aliases | FinGER8; YIP1-interacting factor homolog B; Protein YIF1B |
Chromosomal Location | 19q13.2 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Content |
Distribution of YIF1B expression across immune and molecular subtypes. > Immune subtype > Molecular subtype |
Summary | |
---|---|
Symbol | YIF1B |
Name | Yip1 interacting factor homolog B (S. cerevisiae) |
Aliases | FinGER8; YIP1-interacting factor homolog B; Protein YIF1B |
Chromosomal Location | 19q13.2 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Content |
Associations between YIF1B and clinical features. > Overall survival analysis > Cancer stage > Tumor grade |
Summary | |
---|---|
Symbol | YIF1B |
Name | Yip1 interacting factor homolog B (S. cerevisiae) |
Aliases | FinGER8; YIP1-interacting factor homolog B; Protein YIF1B |
Chromosomal Location | 19q13.2 |
External Links | HGNC, NCBI, Ensembl, Uniprot, GeneCards |
Content | Drugs targeting YIF1B collected from DrugBank database. |
There is no record. |